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Danny Misiak

Explore the profile of Danny Misiak including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 543
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Recent Articles
1.
Schott A, Simon T, Muller S, Rausch A, Busch B, Glass M, et al.
NAR Cancer . 2025 Feb; 7(1):zcaf006. PMID: 40008228
The Hippo/YAP1 signaling pathway regulates normal development by controlling contact inhibition of growth. In cancer, YAP1 activation is often dysregulated, leading to excessive tumor growth and metastasis. SRC kinase can...
2.
Hase N, Misiak D, Taubert H, Huttelmaier S, Gekle M, Kohn M
Mol Oncol . 2024 Aug; 19(1):114-132. PMID: 39183666
Renowned as the predominant form of kidney cancer, clear cell renal cell carcinoma (ccRCC) exhibits susceptibility to immunotherapies due to its specific expression profile as well as notable immune cell...
3.
Hagemann S, Misiak D, Bell J, Fuchs T, Lederer M, Bley N, et al.
Mol Cancer . 2023 May; 22(1):88. PMID: 37246217
Background: Neuroblastoma is the most common solid tumor in infants accounting for approximately 15% of all cancer-related deaths. Over 50% of high-risk neuroblastoma relapse, emphasizing the need of novel drug...
4.
Weisse J, Rosemann J, Muller L, Kappler M, Eckert A, Glass M, et al.
Mol Cancer . 2023 Mar; 22(1):50. PMID: 36918841
No abstract available.
5.
Sperling F, Misiak D, Huttelmaier S, Michl P, Griesmann H
Cancers (Basel) . 2022 May; 14(9). PMID: 35565249
Neuroendocrine neoplasms (NENs) represent a heterogenous class of highly vascularized neoplasms that are increasing in prevalence and are predominantly diagnosed at a metastatic state. The molecular mechanisms leading to tumor...
6.
Misiak D, Bauer M, Lange J, Haase J, Braun J, Lorenz K, et al.
Cancers (Basel) . 2021 Dec; 13(23). PMID: 34885022
Anaplastic thyroid carcinoma (ATC) is the most fatal and rapidly evolving endocrine malignancy invading the head and neck region and accounts for up to 50% of thyroid cancer-associated deaths. Deregulation...
7.
Hupfeld J, Ernst M, Knyrim M, Binas S, Kloeckner U, Rabe S, et al.
Biomedicines . 2021 Jul; 9(7). PMID: 34201741
MicroRNAs (miRs) contribute to different aspects of cardiovascular pathology, among them cardiac hypertrophy and atrial fibrillation. Cardiac miR expression was analyzed in a mouse model with structural and electrical remodeling....
8.
Weisse J, Rosemann J, Muller L, Kappler M, Eckert A, Glass M, et al.
Mol Cancer . 2021 Jun; 20(1):88. PMID: 34116687
Background: Cancer metastases are the main cause of lethality. The five-year survival rate for patients diagnosed with advanced stage oral cancer is 30%. Hence, the identification of novel therapeutic targets...
9.
Misiak D, Hagemann S, Bell J, Busch B, Lederer M, Bley N, et al.
Front Oncol . 2021 May; 11:647737. PMID: 34026620
gene amplification and upregulated expression are major hallmarks in the progression of high-risk neuroblastoma. MYCN expression and function in modulating gene synthesis in neuroblastoma is controlled at virtually every level,...
10.
Glass M, Misiak D, Bley N, Muller S, Hagemann S, Busch B, et al.
Front Mol Biosci . 2021 Apr; 8:632219. PMID: 33829040
The oncofetal IGF2 mRNA-binding protein 1 (IGF2BP1) promotes tumor progression in a variety of solid tumors and its expression is associated with adverse prognosis. The main role proposed for IGF2BP1...