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Bianca Busch

Explore the profile of Bianca Busch including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 332
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Recent Articles
1.
Schott A, Simon T, Muller S, Rausch A, Busch B, Glass M, et al.
NAR Cancer . 2025 Feb; 7(1):zcaf006. PMID: 40008228
The Hippo/YAP1 signaling pathway regulates normal development by controlling contact inhibition of growth. In cancer, YAP1 activation is often dysregulated, leading to excessive tumor growth and metastasis. SRC kinase can...
2.
DeJong S, Brooks D, Khan S, Reaves S, Busch B, Alicata D, et al.
Acad Psychiatry . 2021 Dec; 46(6):740-745. PMID: 34855156
Objective: This report summarizes findings from a 2020 survey of US child and adolescent psychiatry training programs that explored the impact of the COVID-19 pandemic on pediatric telepsychiatry training. The...
3.
Khan S, Myers K, Busch B, Brooks D, Alicata D, Ramtekkar U, et al.
J Child Adolesc Psychopharmacol . 2021 Jul; 31(7):457-463. PMID: 34283939
Our goal was to develop an open access nationally disseminated online curriculum for use in graduate and continuing medical education on the topic of pediatric telepsychiatry to enhance the uptake...
4.
Misiak D, Hagemann S, Bell J, Busch B, Lederer M, Bley N, et al.
Front Oncol . 2021 May; 11:647737. PMID: 34026620
gene amplification and upregulated expression are major hallmarks in the progression of high-risk neuroblastoma. MYCN expression and function in modulating gene synthesis in neuroblastoma is controlled at virtually every level,...
5.
Glass M, Misiak D, Bley N, Muller S, Hagemann S, Busch B, et al.
Front Mol Biosci . 2021 Apr; 8:632219. PMID: 33829040
The oncofetal IGF2 mRNA-binding protein 1 (IGF2BP1) promotes tumor progression in a variety of solid tumors and its expression is associated with adverse prognosis. The main role proposed for IGF2BP1...
6.
Muller S, Bley N, Busch B, Glass M, Lederer M, Misiak C, et al.
Nucleic Acids Res . 2020 Aug; 48(15):8576-8590. PMID: 32761127
The IGF2 mRNA-binding protein 1 (IGF2BP1) is a non-catalytic post-transcriptional enhancer of tumor growth upregulated and associated with adverse prognosis in solid cancers. However, conserved effector pathway(s) and the feasibility...
7.
Muller S, Bley N, Glass M, Busch B, Rousseau V, Misiak D, et al.
Nucleic Acids Res . 2018 Apr; 46(12):6285-6303. PMID: 29660014
The oncofetal IGF2 mRNA binding proteins (IGF2BPs) are upregulated in most cancers but their paralogue-specific roles in tumor cells remain poorly understood. In a panel of five cancer-derived cell lines,...
8.
Busch B, Bley N, Muller S, Glass M, Misiak D, Lederer M, et al.
Nucleic Acids Res . 2016 Feb; 44(8):3845-64. PMID: 26917013
The tumor-suppressive let-7 microRNA family targets various oncogene-encoding mRNAs. We identify the let-7 targets HMGA2, LIN28B and IGF2BP1 to form a let-7 antagonizing self-promoting oncogenic triangle. Surprisingly, 3'-end processing of...
9.
Bretschneider M, Busch B, Mueller D, Nolze A, Schreier B, Gekle M, et al.
FASEB J . 2016 Jan; 30(4):1610-22. PMID: 26728178
Inappropriately activated mineralocorticoid receptor (MR) is a risk factor for vascular remodeling with unclear molecular mechanism. Recent findings suggest that post-transcriptional regulation by micro-RNAs (miRs) may be involved. Our aim...
10.
Braun J, Misiak D, Busch B, Krohn K, Huttelmaier S
Nucleic Acids Res . 2014 Feb; 42(8):e66. PMID: 24510096
MicroRNAs (miRNAs) control gene expression at the post-transcriptional level. However, the identification of miRNAs regulating the fate of a specific messenger RNA remains limited due to the imperfect complementarity of...