Simon Muller
Overview
Explore the profile of Simon Muller including associated specialties, affiliations and a list of published articles.
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Articles
66
Citations
851
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Recent Articles
1.
Schott A, Simon T, Muller S, Rausch A, Busch B, Glass M, et al.
NAR Cancer
. 2025 Feb;
7(1):zcaf006.
PMID: 40008228
The Hippo/YAP1 signaling pathway regulates normal development by controlling contact inhibition of growth. In cancer, YAP1 activation is often dysregulated, leading to excessive tumor growth and metastasis. SRC kinase can...
2.
Caragine C, Le V, Mustafa M, Diaz B, Morris J, Muller S, et al.
Nat Commun
. 2025 Feb;
16(1):1611.
PMID: 39948336
Cis-regulatory elements (CREs), such as enhancers and promoters, are fundamental regulators of gene expression and, across different cell types, the MYC locus utilizes a diverse regulatory architecture driven by multiple...
3.
Hart S, Muller S, Wessels H, Mendez-Mancilla A, Drabavicius G, Choi O, et al.
Nat Biotechnol
. 2025 Feb;
PMID: 39934271
The possibility of collateral RNA degradation poses a concern for transcriptome perturbations and therapeutic applications using CRISPR-Cas13. We show that collateral activity only occurs with high RfxCas13d expression. Using low-copy...
4.
Liang W, Muller S, Hart S, Wessels H, Mendez-Mancilla A, Sookdeo A, et al.
Cell
. 2024 Nov;
187(26):7637-7654.e29.
PMID: 39532094
Mammalian genomes host a diverse array of RNA that includes protein-coding and noncoding transcripts. However, the functional roles of most long noncoding RNAs (lncRNAs) remain elusive. Using RNA-targeting CRISPR-Cas13 screens,...
5.
Knowles L, Wolter C, Linsler S, Muller S, Urbschat S, Ketter R, et al.
Cancer Res Commun
. 2024 Nov;
4(12):3124-3136.
PMID: 39530733
High-grade gliomas are associated with intratumoral thrombosis, tumor cell necrosis, and hemorrhage. The resulting blood clot serves as an adhesive matrix for glioma cell integrins that activate FAK. Knocking down...
6.
Cerminara S, Cvijetic I, Huber S, Muller S, Kostner L, Goessinger E, et al.
J Eur Acad Dermatol Venereol
. 2024 Oct;
PMID: 39445679
No abstract available.
7.
Thull R, Goedicke-Fritz S, Schmiech D, Marnach A, Muller S, Korbel C, et al.
Biosensors (Basel)
. 2024 Sep;
14(9).
PMID: 39329812
(1) Objective: This study aims to lay a foundation for noncontact intensive care monitoring of premature babies. (2) Methods: Arterial oxygen saturation and heart rate were measured using a monochrome...
8.
Muller S, Corbera-Rubio F, Schoonenberg Kegel F, Laureni M, van Loosdrecht M, van Halem D
Water Res
. 2024 Jul;
262:122135.
PMID: 39067270
Rapid sand filters are established and widely applied technologies for groundwater treatment. In these filters, main groundwater contaminants such as iron, manganese, and ammonium are oxidized and removed. Conventionally, intensive...
9.
Hart S, Wessels H, Mendez-Mancilla A, Muller S, Drabavicius G, Choi O, et al.
bioRxiv
. 2024 May;
PMID: 38798586
While CRISPR-Cas13 systems excel in accurately targeting RNA, the potential for collateral RNA degradation poses a concern for therapeutic applications and limits broader adoption for transcriptome perturbations. We evaluate the...
10.
Muller S, Jain M, Sachdeva B, Shah P, Holz F, Finger R, et al.
Transl Vis Sci Technol
. 2024 Apr;
13(4):20.
PMID: 38618893
Purpose: The purpose of this study was to assess the current use and reliability of artificial intelligence (AI)-based algorithms for analyzing cataract surgery videos. Methods: A systematic review of the...