Danny Barash
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Explore the profile of Danny Barash including associated specialties, affiliations and a list of published articles.
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60
Citations
392
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Recent Articles
1.
Mukherjee S, Mukherjee S, Barash D
Methods Mol Biol
. 2024 Sep;
2847:193-204.
PMID: 39312145
Riboswitches are naturally occurring regulatory segments of RNA molecules that modulate gene expression in response to specific ligand binding. They serve as a molecular 'switch' that controls the RNA's structure...
2.
Zakh R, Churkin A, Barash D
Methods Mol Biol
. 2024 Sep;
2847:109-120.
PMID: 39312139
Computational RNA design was introduced in the 1990s by Vienna's RNAinverse, which is a simple inverse RNA folding solver. Further developments and contemporary RNA design techniques, in addition to improved...
3.
Mukherjee S, Barash D
Trends Biotechnol
. 2023 Dec;
42(5):517-521.
PMID: 38040620
RNA switches respond to specific ligands to control gene expression. They are widely used in synthetic biology applications and hold potential for future RNA-based therapeutic breakthroughs. However, the crux is...
4.
Hailegiorgis A, Ishida Y, Collier N, Imamura M, Shi Z, Reinharz V, et al.
PLoS Comput Biol
. 2023 Aug;
19(8):e1011309.
PMID: 37535676
Hepatitis B virus (HBV) infection kinetics in immunodeficient mice reconstituted with humanized livers from inoculation to steady state is highly dynamic despite the absence of an adaptive immune response. To...
5.
Mukherjee S, Retwitzer M, Hubbell S, Meyer M, Barash D
Brief Bioinform
. 2023 Mar;
24(3).
PMID: 36951499
Riboswitches are conserved structural ribonucleic acid (RNA) sensors that are mainly found to regulate a large number of genes/operons in bacteria. Presently, >50 bacterial riboswitch classes have been discovered, but...
6.
Mhlanga A, Zakh R, Churkin A, Reinharz V, Glenn J, Etzion O, et al.
Mathematics (Basel)
. 2022 Dec;
10(20).
PMID: 36540372
Hepatitis D virus is an infectious subviral agent that can only propagate in people infected with hepatitis B virus. In this study, we modified and further developed a recent model...
7.
Reinharz V, Churkin A, Dahari H, Barash D
Mathematics (Basel)
. 2022 Oct;
10(12).
PMID: 36245949
Mathematical models, some of which incorporate both intracellular and extracellular hepatitis C viral kinetics, have been advanced in recent years for studying HCV-host dynamics, antivirals mode of action, and their...
8.
Churkin A, Ponty Y, Barash D
BMC Bioinformatics
. 2022 Oct;
23(Suppl 8):424.
PMID: 36241988
Background: RNA deleterious point mutation prediction was previously addressed with programs such as RNAmute and MultiRNAmute. The purpose of these programs is to predict a global conformational rearrangement of the...
9.
Mukherjee S, Kuang Z, Ghosh S, Detroja R, Carmi G, Tripathy S, et al.
Biology (Basel)
. 2022 Jul;
11(8).
PMID: 35892966
Soil bacteria respond rapidly to changes in new environmental conditions. For adaptation to the new environment, they could mutate their genome, which impacts the alternation of the functional and regulatory...
10.
Goyal A, Churkin A, Barash D, Cotler S, Shlomai A, Etzion O, et al.
Open Forum Infect Dis
. 2022 May;
9(5):ofac157.
PMID: 35493122
Shortening duration of direct-acting antiviral therapy for chronic hepatitis C could provide cost savings, reduce medication exposure, and foster adherence and treatment completion in special populations. The current analysis indicates...