Danielle Versteeg
Overview
Explore the profile of Danielle Versteeg including associated specialties, affiliations and a list of published articles.
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17
Citations
588
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Recent Articles
1.
Timmer L, den Hertog E, Versteeg D, Post H, Verdonschot J, Monshouwer-Kloots J, et al.
Cardiovasc Res
. 2025 Feb;
PMID: 39957251
Aims: In this study, we aimed to uncover genes associated with stressed cardiomyocytes by combining single-cell transcriptomic datasets from failing cardiac tissue from both humans and mice. Methods And Results:...
2.
Bouwman M, de Bakker D, Honkoop H, Giovou A, Versteeg D, Boender A, et al.
Nat Cardiovasc Res
. 2025 Jan;
4(1):64-82.
PMID: 39747457
In contrast to adult mammalian hearts, the adult zebrafish heart efficiently replaces cardiomyocytes lost after injury. Here we reveal shared and species-specific injury response pathways and a correlation between Hmga1,...
3.
Gladka M, Kohela A, de Leeuw A, Molenaar B, Versteeg D, Kooijman L, et al.
Cardiovasc Res
. 2024 Sep;
120(15):1869-1883.
PMID: 39308239
Aims: Intracellular calcium (Ca2+) overload is known to play a critical role in the development of cardiac dysfunction. Despite the remarkable improvement in managing the progression of heart disease, developing...
4.
Kyriakopoulou E, Versteeg D, de Ruiter H, Perini I, Seibertz F, Doring Y, et al.
Nat Cardiovasc Res
. 2024 Apr;
2(12):1262-1276.
PMID: 38665939
Arrhythmogenic cardiomyopathy is a severe cardiac disorder characterized by lethal arrhythmias and sudden cardiac death, with currently no effective treatment. Plakophilin 2 () is the most frequently affected gene. Here...
5.
Boogerd C, Perini I, Kyriakopoulou E, Han S, La P, van der Swaan B, et al.
Nat Commun
. 2023 Aug;
14(1):4716.
PMID: 37543677
The inability of adult human cardiomyocytes to proliferate is an obstacle to efficient cardiac regeneration after injury. Understanding the mechanisms that drive postnatal cardiomyocytes to switch to a non-regenerative state...
6.
Tsui H, van Kampen S, Han S, Meraviglia V, van Ham W, Casini S, et al.
Sci Transl Med
. 2023 Mar;
15(688):eadd4248.
PMID: 36947592
Arrhythmogenic cardiomyopathy (ACM) is an inherited progressive cardiac disease. Many patients with ACM harbor mutations in desmosomal genes, predominantly in plakophilin-2 (). Although the genetic basis of ACM is well...
7.
Gladka M, Johansen A, van Kampen S, Peters M, Molenaar B, Versteeg D, et al.
Cardiovasc Res
. 2022 Sep;
119(3):802-812.
PMID: 36125329
Aims: The adult mammalian heart is a post-mitotic organ. Even in response to necrotic injuries, where regeneration would be essential to reinstate cardiac structure and function, only a minor percentage...
8.
Boogerd C, Lacraz G, Vertesy A, van Kampen S, Perini I, de Ruiter H, et al.
Cardiovasc Res
. 2022 May;
119(2):477-491.
PMID: 35576477
Aims: Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that is characterized by progressive loss of myocardium that is replaced by fibro-fatty cells, arrhythmias, and sudden cardiac death. While myocardial...
9.
Koopmans T, van Beijnum H, Roovers E, Tomasso A, Malhotra D, Boeter J, et al.
NPJ Regen Med
. 2021 Nov;
6(1):78.
PMID: 34789755
Ischemic heart disease and by extension myocardial infarction is the primary cause of death worldwide, warranting regenerative therapies to restore heart function. Current models of natural heart regeneration are restricted...
10.
Molenaar B, Timmer L, Droog M, Perini I, Versteeg D, Kooijman L, et al.
Commun Biol
. 2021 Jan;
4(1):146.
PMID: 33514846
The efficiency of the repair process following ischemic cardiac injury is a crucial determinant for the progression into heart failure and is controlled by both intra- and intercellular signaling within...