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Danielle Versteeg

Explore the profile of Danielle Versteeg including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 588
Followers 0
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Recent Articles
11.
Gladka M, Kohela A, Molenaar B, Versteeg D, Kooijman L, Monshouwer-Kloots J, et al.
Nat Commun . 2021 Jan; 12(1):84. PMID: 33398012
The disruption in blood supply due to myocardial infarction is a critical determinant for infarct size and subsequent deterioration in function. The identification of factors that enhance cardiac repair by...
12.
Vigil-Garcia M, Demkes C, Eding J, Versteeg D, de Ruiter H, Perini I, et al.
Cardiovasc Res . 2020 Jul; 117(6):1532-1545. PMID: 32717063
Aims: Pathological cardiac remodelling is characterized by cardiomyocyte (CM) hypertrophy and fibroblast activation, which can ultimately lead to maladaptive hypertrophy and heart failure (HF). Genome-wide expression analysis on heart tissue...
13.
Kretzschmar K, Post Y, Bannier-Helaouet M, Mattiotti A, Drost J, Basak O, et al.
Proc Natl Acad Sci U S A . 2018 Dec; 115(52):E12245-E12254. PMID: 30530645
The significance of cardiac stem cell (CSC) populations for cardiac regeneration remains disputed. Here, we apply the most direct definition of stem cell function (the ability to replace lost tissue...
14.
Gladka M, Molenaar B, de Ruiter H, van der Elst S, Tsui H, Versteeg D, et al.
Circulation . 2018 Feb; 138(2):166-180. PMID: 29386203
Background: Genome-wide transcriptome analysis has greatly advanced our understanding of the regulatory networks underlying basic cardiac biology and mechanisms driving disease. However, so far, the resolution of studying gene expression...
15.
Johansen A, Molenaar B, Versteeg D, Leitoguinho A, Demkes C, Spanjaard B, et al.
Circ Res . 2017 Aug; 121(10):1168-1181. PMID: 28851809
Rationale: CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated protein 9)-based DNA editing has rapidly evolved as an attractive tool to modify the genome. Although CRISPR/Cas9 has been extensively used to manipulate...
16.
Lacraz G, Junker J, Gladka M, Molenaar B, Scholman K, Vigil-Garcia M, et al.
Circulation . 2017 Jul; 136(15):1396-1409. PMID: 28724751
Background: Cardiac ischemic injury induces a pathological remodeling response, which can ultimately lead to heart failure. Detailed mechanistic insights into molecular signaling pathways relevant for different aspects of cardiac remodeling...
17.
Wisniewska-Kruk J, van der Wijk A, van Veen H, Gorgels T, Vogels I, Versteeg D, et al.
Am J Pathol . 2016 Feb; 186(4):1044-54. PMID: 26878208
Loss of blood-retinal barrier (BRB) properties induced by vascular endothelial growth factor (VEGF) and other factors is an important cause of diabetic macular edema. Previously, we found that the presence...
18.
Gorgels T, Waarsing J, Herfs M, Versteeg D, Schoensiegel F, Sato T, et al.
J Mol Med (Berl) . 2011 Jul; 89(11):1125-35. PMID: 21725681
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder in which calcification of connective tissue leads to pathology in skin, eye and blood vessels. PXE is caused by mutations in ABCC6....