Danielle Duquette
Overview
Explore the profile of Danielle Duquette including associated specialties, affiliations and a list of published articles.
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9
Citations
938
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Recent Articles
1.
Harmon C, Zaborowski A, Moore H, St Louis P, Slattery K, Duquette D, et al.
Nat Cancer
. 2023 Jul;
4(8):1122-1137.
PMID: 37474835
γδ T cells are important tissue-resident, innate T cells that are critical for tissue homeostasis. γδ cells are associated with positive prognosis in most tumors; however, little is known about...
2.
Duquette D, Harmon C, Zaborowski A, Michelet X, OFarrelly C, Winter D, et al.
J Immunol
. 2023 Jul;
211(4):633-647.
PMID: 37449888
NK cells and CD8 T cells use cytotoxic molecules to kill virally infected and tumor cell targets. While perforin and granzyme B (GzmB) are the most commonly studied lytic molecules,...
3.
Kohlgruber A, Gal-Oz S, LaMarche N, Shimazaki M, Duquette D, Koay H, et al.
Nat Immunol
. 2019 Feb;
20(3):373.
PMID: 30728493
In the version of this article initially published, three authors (Hui-Fern Kuoy, Adam P. Uldrich and Dale. I. Godfrey) and their affiliations, acknowledgments and contributions were not included. The correct...
4.
Michelet X, Dyck L, Hogan A, Loftus R, Duquette D, Wei K, et al.
Nat Immunol
. 2018 Nov;
19(12):1330-1340.
PMID: 30420624
Up to 49% of certain types of cancer are attributed to obesity, and potential mechanisms include overproduction of hormones, adipokines, and insulin. Cytotoxic immune cells, including natural killer (NK) cells...
5.
Wu D, Hu D, Chen H, Shi G, Fetahu I, Wu F, et al.
Nature
. 2018 Jul;
559(7715):637-641.
PMID: 30022161
Diabetes is a complex metabolic syndrome that is characterized by prolonged high blood glucose levels and frequently associated with life-threatening complications. Epidemiological studies have suggested that diabetes is also linked...
6.
Kohlgruber A, Gal-Oz S, LaMarche N, Shimazaki M, Duquette D, Koay H, et al.
Nat Immunol
. 2018 Apr;
19(5):464-474.
PMID: 29670241
γδ T cells are situated at barrier sites and guard the body from infection and damage. However, little is known about their roles outside of host defense in nonbarrier tissues....
7.
Chang S, Kohlgruber A, Mizoguchi F, Michelet X, Wolf B, Wei K, et al.
J Clin Invest
. 2017 Aug;
127(9):3300-3312.
PMID: 28758901
M2 macrophages, innate lymphoid type 2 cells (ILC2s), eosinophils, Tregs, and invariant NK T cells (iNKT cells) all help to control adipose tissue inflammation, while M1 macrophages, TNF, and other...
8.
Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity
Boulenouar S, Michelet X, Duquette D, Alvarez D, Hogan A, Dold C, et al.
Immunity
. 2017 Feb;
46(2):273-286.
PMID: 28228283
Adipose tissue has a dynamic immune system that adapts to changes in diet and maintains homeostatic tissue remodeling. Adipose type 1 innate lymphoid cells (AT1-ILCs) promote pro-inflammatory macrophages in obesity,...
9.
Lynch L, Hogan A, Duquette D, Lester C, Banks A, Leclair K, et al.
Cell Metab
. 2016 Sep;
24(3):510-519.
PMID: 27593966
Adipose-resident invariant natural killer T (iNKT) cells are key players in metabolic regulation. iNKT cells are innate lipid sensors, and their activation, using their prototypic ligand α-galactosylceramide (αGalCer), induces weight...