Daniela Valeria Miniero
Overview
Explore the profile of Daniela Valeria Miniero including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
203
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Recent Articles
1.
Miniero D, Palmieri F, Quadrotta V, Polticelli F, Palmieri L, Monne M
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769317
Mitochondrial carriers transport organic acids, amino acids, nucleotides and cofactors across the mitochondrial inner membrane. These transporters consist of a three-fold symmetric bundle of six transmembrane α-helices that encircle a...
2.
Spagnoletta A, Miniero D, Gambacorta N, Oppedisano F, De Grassi A, Nicolotti O, et al.
Molecules
. 2024 Nov;
29(21).
PMID: 39519794
The 2-oxoglutarate carrier (OGC), pivotal in cellular metabolism, facilitates the exchange of key metabolites between mitochondria and cytosol. This study explores the influence of NADPH on OGC transport activity using...
3.
Ferraro V, Spagnoletta A, Rotondo N, Marsano R, Miniero D, Balenzano G, et al.
J Fungi (Basel)
. 2024 Oct;
10(10).
PMID: 39452670
Type-2 diabetes affects an increasing percentage of the world's population and its control through dietary management, involving the consumption of health-promoting foods or their derived supplements, is a common strategy....
4.
La Spada G, Miniero D, Rullo M, Cipolloni M, Delre P, Colliva C, et al.
Eur J Med Chem
. 2024 May;
274:116511.
PMID: 38820854
A structure-based drug design approach was focused on incorporating phenyl ring heterocyclic bioisosteres into coumarin derivative 1, previously reported as potent dual AChE-MAO B inhibitor, with the aim of improving...
5.
Samarelli F, Purgatorio R, Lopopolo G, Deruvo C, Catto M, Andresini M, et al.
Eur J Med Chem
. 2024 Apr;
270:116353.
PMID: 38579622
Due to the putative role of butyrylcholinesterase (BChE) in regulation of acetylcholine levels and functions in the late stages of the Alzheimer's disease (AD), the potential of selective inhibitors (BChEIs)...
6.
Al-Saad O, Gabr M, Darwish S, Rullo M, Pisani L, Miniero D, et al.
Eur J Med Chem
. 2024 Mar;
269:116266.
PMID: 38490063
In neurodegenerative diseases, using a single molecule that can exert multiple effects to modify the disease may have superior activity over the classical "one molecule-one target" approach. Herein, we describe...
7.
Latronico T, Rossano R, Miniero D, Casalino E, Liuzzi G
Int J Mol Sci
. 2024 Feb;
25(4).
PMID: 38396818
Chronic exposure to manganese (Mn) leads to its accumulation in the central nervous system (CNS) and neurotoxicity with not well-known mechanisms. We investigated the involvement of matrix metalloproteinase (MMP)-2 and...
8.
Pasquadibisceglie A, Bonaccorsi di Patti M, Miniero D, Musci G, Polticelli F
Front Mol Biosci
. 2023 Nov;
10:1323824.
PMID: 38028551
No abstract available.
9.
Milani G, Budriesi R, Tavazzani E, Cavalluzzi M, Mattioli L, Miniero D, et al.
Arch Pharm (Weinheim)
. 2023 Jul;
356(10):e2300116.
PMID: 37460390
Long QT syndrome (LQTS) is a disorder of cardiac electrophysiology resulting in life-threatening arrhythmias; nowadays, only a few drugs are available for the management of LQTS. Focusing our attention on...
10.
Rullo M, La Spada G, Miniero D, Gottinger A, Catto M, Delre P, et al.
Eur J Med Chem
. 2023 May;
255:115352.
PMID: 37178666
Following a hybridization strategy, a series of 5-substituted-1H-indazoles were designed and evaluated in vitro as inhibitors of human monoamine oxidase (hMAO) A and B. Among structural modifications, the bioisostere-based introduction...