Daniela S Dimitrova
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Explore the profile of Daniela S Dimitrova including associated specialties, affiliations and a list of published articles.
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7
Citations
793
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Recent Articles
1.
Dimitrova D
J Cell Sci
. 2011 Aug;
124(Pt 16):2743-52.
PMID: 21807939
Typically, only a fraction of the ≥600 ribosomal RNA (rRNA) gene copies in human cells are transcriptionally active. Expressed rRNA genes coalesce in specialized nuclear compartments - the nucleoli -...
2.
Harrigan J, Belotserkovskaya R, Coates J, Dimitrova D, Polo S, Bradshaw C, et al.
J Cell Biol
. 2011 Mar;
193(1):97-108.
PMID: 21444690
Chromosomal deletions and rearrangements in tumors are often associated with common fragile sites, which are specific genomic loci prone to gaps and breaks in metaphase chromosomes. Common fragile sites appear...
3.
Schoenfelder S, Sexton T, Chakalova L, Cope N, Horton A, Andrews S, et al.
Nat Genet
. 2009 Dec;
42(1):53-61.
PMID: 20010836
The discovery of interchromosomal interactions in higher eukaryotes points to a functional interplay between genome architecture and gene expression, challenging the view of transcription as a one-dimensional process. However, the...
4.
Dimitrova D
Methods Mol Biol
. 2009 Jul;
521:413-36.
PMID: 19563120
DNA replication takes place at discrete sites in the cell nucleus, named replication foci. The spatial arrangements of these foci change in the course of S phase in a temporally...
5.
Dimitrova D
Genes Cells
. 2006 Jul;
11(7):829-44.
PMID: 16824201
I have demonstrated that nuclear transcription modulates the distribution of replication origins along mammalian chromosomes. Chinese Hamster Ovary (CHO) cells were exposed to transcription inhibitors in early G1 phase and...
6.
Dimitrova D, Berezney R
J Cell Sci
. 2002 Oct;
115(Pt 21):4037-51.
PMID: 12356909
We investigated the organization of DNA replication sites in primary (young or presenescent), immortalized and transformed mammalian cells. Four different methods were used to visualize replication sites: in vivo pulse-labeling...
7.
Dimitrova D, Prokhorova T, Blow J, Todorov I, Gilbert D
J Cell Sci
. 2002 Jan;
115(Pt 1):51-9.
PMID: 11801723
Mcm 2-7 are essential replication proteins that bind to chromatin in mammalian nuclei during late telophase. Here, we have investigated the relationship between Mcm binding, licensing of chromatin for replication,...