Daniel Strebinger
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Explore the profile of Daniel Strebinger including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
133
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Recent Articles
1.
Zilberzwige-Tal S, Altae-Tran H, Kannan S, Wilkinson M, Vo S, Strebinger D, et al.
Cell
. 2025 Feb;
PMID: 39970912
Despite ongoing efforts to study CRISPR systems, the evolutionary origins giving rise to reprogrammable RNA-guided mechanisms remain poorly understood. Here, we describe an integrated sequence/structure evolutionary tracing approach to identify...
2.
Raghavan R, Friedrich M, King I, Vo S, Strebinger D, Lash B, et al.
Nat Commun
. 2025 Jan;
16(1):105.
PMID: 39747875
Genome editing using CRISPR-Cas systems is a promising avenue for the treatment of genetic diseases. However, cellular and humoral immunogenicity of genome editing tools, which originate from bacteria, complicates their...
3.
Frangieh C, Wilkinson M, Strebinger D, Strecker J, Walsh M, Faure G, et al.
Mob DNA
. 2024 Jun;
15(1):12.
PMID: 38863000
Eukaryotic retroelements are generally divided into two classes: long terminal repeat (LTR) retrotransposons and non-LTR retrotransposons. A third class of eukaryotic retroelement, the Penelope-like elements (PLEs), has been well-characterized bioinformatically,...
4.
Gewurz B, Guo R, Lim M, Shah H, Paulo J, Zhang Y, et al.
Res Sq
. 2024 Jun;
PMID: 38854072
B-lymphocytes play major adaptive immune roles, producing antibody and driving T-cell responses. However, how immunometabolism networks support B-cell activation and differentiation in response to distinct receptor stimuli remains incompletely understood....
5.
Normandin E, Triana S, Raju S, Lan T, Lagerborg K, Rudy M, et al.
Cell Genom
. 2024 Jan;
3(12):100440.
PMID: 38169842
Ebola virus (EBOV) causes Ebola virus disease (EVD), marked by severe hemorrhagic fever; however, the mechanisms underlying the disease remain unclear. To assess the molecular basis of EVD across time,...
6.
Strebinger D, Frangieh C, Friedrich M, Faure G, Macrae R, Zhang F
Nat Commun
. 2023 Aug;
14(1):5141.
PMID: 37612276
The delivery of genetic cargo remains one of the largest obstacles to the successful translation of experimental therapies, in large part due to the absence of targetable delivery vectors. Enveloped...
7.
Chabloz A, Schaefer J, Kozieradzki I, Cronin S, Strebinger D, Macaluso F, et al.
Commun Biol
. 2020 Jul;
3(1):342.
PMID: 32620833
Protein-based affinity reagents (like antibodies or alternative binding scaffolds) offer wide-ranging applications for basic research and therapeutic approaches. However, whereas small chemical molecules efficiently reach intracellular targets, the delivery of...
8.
Strebinger D, Deluz C, Friman E, Govindan S, Alber A, Suter D
Mol Syst Biol
. 2019 Sep;
15(9):e9002.
PMID: 31556488
SOX2 and OCT4 are pioneer transcription factors playing a key role in embryonic stem (ES) cell self-renewal and differentiation. How temporal fluctuations in their expression levels bias lineage commitment is...
9.
Deluz C, Strebinger D, Friman E, Suter D
Cell Cycle
. 2017 Feb;
16(7):601-606.
PMID: 28166426
The ability of some transcription factors to remain bound to specific genes on condensed mitotic chromosomes has been suggested to play a role in their rapid transcriptional reactivation upon mitotic...
10.
Deluz C, Friman E, Strebinger D, Benke A, Raccaud M, Callegari A, et al.
Genes Dev
. 2016 Dec;
30(22):2538-2550.
PMID: 27920086
Mitotic bookmarking transcription factors remain bound to chromosomes during mitosis and were proposed to regulate phenotypic maintenance of stem and progenitor cells at the mitosis-to-G1 (M-G1) transition. However, mitotic bookmarking...