Daniel P Caron
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Explore the profile of Daniel P Caron including associated specialties, affiliations and a list of published articles.
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11
Citations
86
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Recent Articles
1.
Szabo P, Levitin H, Connors T, Chen D, Jin J, Thapa P, et al.
bioRxiv
. 2025 Feb;
PMID: 39974963
The first years of life are essential for the development of memory T cells, which rapidly populate the body's diverse tissue sites during infancy. However, the degree to which tissue...
2.
Caron D, Specht W, Chen D, Wells S, Szabo P, Jensen I, et al.
Cell Rep Methods
. 2025 Jan;
5(1):100938.
PMID: 39814026
Single-cell RNA sequencing (scRNA-seq) is invaluable for profiling cellular heterogeneity and transcriptional states, but transcriptomic profiles do not always delineate subsets defined by surface proteins. Cellular indexing of transcriptomes and...
3.
Davis-Porada J, George A, Lam N, Caron D, Gray J, Huang J, et al.
Immunity
. 2024 Nov;
57(12):2895-2913.e8.
PMID: 39510068
Memory T and B cells in tissues are essential for protective immunity. Here, we performed a comprehensive analysis of the tissue distribution, phenotype, durability, and transcriptional profile of COVID-19 mRNA...
4.
Zheng Y, Caron D, Kim J, Jun S, Tian Y, Florian M, et al.
Res Sq
. 2024 Jul;
PMID: 39041028
CITE-seq enables paired measurement of surface protein and mRNA expression in single cells using antibodies conjugated to oligonucleotide tags. Due to the high copy number of surface protein molecules, sequencing...
5.
Verma S, Bradley M, Gray J, Dogra P, Caron D, Maurrasse S, et al.
J Immunol
. 2024 Jun;
213(3):306-316.
PMID: 38905110
CD4+ regulatory T cells (Tregs) are key orchestrators of the immune system, fostering the establishment of protective immunity while preventing deleterious responses. Infancy and childhood are crucial periods of rapid...
6.
Gray J, Caron D, Wells S, Guyer R, Szabo P, Rainbow D, et al.
Sci Immunol
. 2024 Jun;
9(96):eadn3954.
PMID: 38848342
During ontogeny, γδ T cells emerge from the thymus and directly seed peripheral tissues for in situ immunity. However, their functional role in humans has largely been defined from blood....
7.
Wells S, Rainbow D, Mark M, Szabo P, Ergen C, Maceiras A, et al.
bioRxiv
. 2024 Jan;
PMID: 38260588
The immune system comprises multiple cell lineages and heterogeneous subsets found in blood and tissues throughout the body. While human immune responses differ between sites and over age, the underlying...
8.
Caron D, Specht W, Chen D, Wells S, Szabo P, Jensen I, et al.
bioRxiv
. 2023 Jul;
PMID: 37461466
Single-cell RNA sequencing (scRNA-seq) is invaluable for profiling cellular heterogeneity and dissecting transcriptional states, but transcriptomic profiles do not always delineate subsets defined by surface proteins, as in cells of...
9.
Poon M, Caron D, Wang Z, Wells S, Chen D, Meng W, et al.
Nat Immunol
. 2023 Jan;
24(2):309-319.
PMID: 36658238
T lymphocytes migrate to barrier sites after exposure to pathogens, providing localized immunity and long-term protection. Here, we obtained blood and tissues from human organ donors to examine T cells...
10.
Ural B, Caron D, Dogra P, Wells S, Szabo P, Granot T, et al.
Nat Med
. 2022 Nov;
28(12):2622-2632.
PMID: 36411343
Older people are particularly susceptible to infectious and neoplastic diseases of the lung and it is unclear how lifelong exposure to environmental pollutants affects respiratory immune function. In an analysis...