Daniel Mar
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Explore the profile of Daniel Mar including associated specialties, affiliations and a list of published articles.
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Citations
329
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Recent Articles
1.
Kumari P, Friedman R, Pi L, Curtis S, Paraiso K, Visel A, et al.
bioRxiv
. 2025 Mar;
PMID: 40027800
Oral facial cleft (OFC) is a multifactorial disorder that can present as a cleft lip with or without cleft palate (CL/P) or a cleft palate only. Genome wide association studies...
2.
Rahimov F, Nieminen P, Kumari P, Juuri E, Nikopensius T, Paraiso K, et al.
Nat Commun
. 2024 Nov;
15(1):9568.
PMID: 39500877
In Finland, the frequency of isolated cleft palate (CP) is higher than that of isolated cleft lip with or without cleft palate (CL/P). This trend contrasts to that in other...
3.
Bomsztyk K, Mar D, Denisenko O, Powell S, Vishnoi M, Yin Z, et al.
Lab Invest
. 2024 Oct;
104(12):102160.
PMID: 39426568
Precision oncology is driven by biomarkers. For glioblastoma multiforme (GBM), the most common malignant adult primary brain tumor, O-methylguanine-DNA methyltransferase (MGMT) gene promoter methylation is an important prognostic and treatment...
4.
Rahimov F, Nieminen P, Kumari P, Juuri E, Nikopensius T, Paraiso K, et al.
medRxiv
. 2024 Jul;
PMID: 39040165
In Finland the frequency of isolated cleft palate (CP) is higher than that of isolated cleft lip with or without cleft palate (CL/P). This trend contrasts to that in other...
5.
Bomsztyk K, Mar D, Denisenko O, Powell S, Vishnoi M, Delegard J, et al.
bioRxiv
. 2024 Apr;
PMID: 38586048
Precision oncology is driven by molecular biomarkers. For glioblastoma multiforme (GBM), the most common malignant adult primary brain tumor, O6-methylguanine-DNA methyltransferase ( ) gene DNA promoter methylation is an important...
6.
Mar D, Babenko I, Zhang R, Noble W, Denisenko O, Vaisar T, et al.
Lab Invest
. 2023 Nov;
104(1):100282.
PMID: 37924947
Large-scale high-dimensional multiomics studies are essential to unravel molecular complexity in health and disease. We developed an integrated system for tissue sampling (CryoGrid), analytes preparation (PIXUL), and downstream multiomic analysis...
7.
Schactler S, Scheuerman S, Lius A, Altemeier W, An D, Matula T, et al.
BMC Genomics
. 2023 Aug;
24(1):446.
PMID: 37553584
Background: Disease molecular complexity requires high throughput workflows to map disease pathways through analysis of vast tissue repositories. Great progress has been made in tissue multiomics analytical technologies. To match...
8.
Mar D, Babenko I, Zhang R, Noble W, Denisenko O, Vaisar T, et al.
bioRxiv
. 2023 Mar;
PMID: 36993219
Background: The multiome is an integrated assembly of distinct classes of molecules and molecular properties, or "omes," measured in the same biospecimen. Freezing and formalin-fixed paraffin-embedding (FFPE) are two common...
9.
Levy S, Somasundaram L, Xavier Raj I, Ic-Mex D, Phal A, Schmidt S, et al.
Cell Rep
. 2022 Mar;
38(9):110457.
PMID: 35235780
Bifurcation of cellular fates, a critical process in development, requires histone 3 lysine 27 methylation (H3K27me3) marks propagated by the polycomb repressive complex 2 (PRC2). However, precise chromatin loci of...
10.
Rumienczyk I, Kulecka M, Ostrowski J, Mar D, Bomsztyk K, Standage S, et al.
J Inflamm Res
. 2021 Jun;
14:2377-2388.
PMID: 34113146
Purpose: During sepsis, an excessive inflammatory immune reaction contributes to multi-organ dysfunction syndrome (MODS), a critical condition associated with high morbidity and mortality; however, the molecular mechanisms driving MODS remain...