Daniel Lindner
Overview
Explore the profile of Daniel Lindner including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
1062
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0
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Recent Articles
1.
Huang S, DiFilippo F, Lindner D, Heston W
Eur J Nucl Med Mol Imaging
. 2023 Jul;
50(10):2950-2951.
PMID: 37395801
No abstract available.
2.
Guan Y, Hasipek M, Jiang D, Tiwari A, Grabowski D, Pagliuca S, et al.
J Clin Invest
. 2022 Jan;
132(4).
PMID: 35085104
Eltrombopag, an FDA-approved non-peptidyl thrombopoietin receptor agonist, is clinically used for the treatment of aplastic anemia, a disease characterized by hematopoietic stem cell failure and pancytopenia, to improve platelet counts...
3.
Gu X, Enane F, Tohme R, Schuerger C, Radivoyevitch T, Parker Y, et al.
Cell Rep
. 2021 Sep;
36(12):109747.
PMID: 34551289
PBRM1, a subunit of the PBAF coactivator complex that transcription factors use to activate target genes, is genetically inactivated in almost all clear cell renal cell cancers (RCCs). Using unbiased...
4.
Hill B, Jagadeesh D, Pohlman B, Dean R, Parameswaran N, Chen J, et al.
Semin Hematol
. 2021 Jan;
58(1):35-44.
PMID: 33509441
One mechanism by which lymphoid malignancies resist standard apoptosis-intending (cytotoxic) treatments is genetic attenuation of the p53/p16-CDKN2A apoptosis axis. Depletion of the epigenetic protein DNA methyltransferase 1 (DNMT1) using the...
5.
Sohal D, Krishnamurthi S, Tohme R, Gu X, Lindner D, Landowski T, et al.
Am J Cancer Res
. 2020 Oct;
10(9):3047-3060.
PMID: 33042633
DNA methyltransferase 1 (DNMT1) is scientifically validated as a molecular target to treat chemo-resistant pancreatic ductal adenocarcinoma (PDAC). Results of clinical studies of the pyrimidine nucleoside analog decitabine to target...
6.
Proudfit A, Bhunia N, Pore D, Parker Y, Lindner D, Gupta N
Sarcoma
. 2020 Oct;
2020:9010496.
PMID: 33005093
Intermediate and high-risk rhabdomyosarcoma (RMS) patients have poor prognosis with available treatment options, highlighting a clear unmet need for identification of novel therapeutic strategies. Ezrin-radixin-moesin (ERM) family members are membrane-cytoskeleton...
7.
Maynard D, Bradford M, Covey K, Lindner D, Glaeser J, Talbert D, et al.
Nat Microbiol
. 2019 Feb;
4(5):846-853.
PMID: 30804547
Fungi are the primary agents of terrestrial decomposition, yet our understanding of fungal biogeography lags far behind that of plants, animals and bacteria. Here, we use a trait-based approach to...
8.
Burger D, Parker Y, Guinta K, Lindner D
Biol Blood Marrow Transplant
. 2017 Nov;
24(2):260-266.
PMID: 29128556
Graft-versus-host disease (GVHD) is a prevalent and potentially lethal complication of hematopoietic stem cell transplantation. Humanized mouse models of xenogeneic GVHD are important tools used to study the human immune...
9.
Justo A, Miettinen O, Floudas D, Ortiz-Santana B, Sjokvist E, Lindner D, et al.
Fungal Biol
. 2017 Aug;
121(9):798-824.
PMID: 28800851
Polyporales is strongly supported as a clade of Agaricomycetes, but the lack of a consensus higher-level classification within the group is a barrier to further taxonomic revision. We amplified nrLSU,...
10.
Yao P, Wu J, Lindner D, Fox P
Nucleic Acids Res
. 2017 May;
45(13):7950-7964.
PMID: 28520992
MicroRNAs (miRNAs) and heterogeneous nuclear ribonucleoproteins (hnRNPs) are families of sequence-specific, posttranscriptional modulators of gene expression. Despite extensive mechanistic and functional studies on both regulatory classes, the interactions and crosstalk...