Daniel K Baeschlin
Overview
Explore the profile of Daniel K Baeschlin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
98
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Schuffenhauer A, Schneider N, Hintermann S, Auld D, Blank J, Cotesta S, et al.
J Med Chem
. 2020 Nov;
63(23):14425-14447.
PMID: 33140646
This article summarizes the evolution of the screening deck at the Novartis Institutes for BioMedical Research (NIBR). Historically, the screening deck was an assembly of all available compounds. In 2015,...
2.
Canham S, Wang Y, Cornett A, Auld D, Baeschlin D, Patoor M, et al.
Cell Chem Biol
. 2020 Jul;
27(9):1124-1129.
PMID: 32707038
Chemogenetic libraries, collections of well-defined chemical probes, provide tremendous value to biomedical research but require substantial effort to ensure diversity as well as quality of the contents. We have assembled...
3.
Baeschlin D, Chaperon A, Charbonneau V, Green L, Ley S, Lucking U, et al.
Angew Chem Int Ed Engl
. 2018 May;
37(24):3423-3428.
PMID: 29711276
Six building blocks, six reaction steps: The recently developed innovative methodology facilitated the convergent synthesis of the complex oligosaccharide core 1 (shown here with protecting groups) for the total synthesis...
4.
Namoto K, Sirockin F, Ostermann N, Gessier F, Flohr S, Sedrani R, et al.
Bioorg Med Chem Lett
. 2014 Jan;
24(3):731-6.
PMID: 24439847
The successful launches of dipeptidyl peptidase IV (DPP IV) inhibitors as oral anti-diabetics warrant and spur the further quest for additional chemical entities in this promising class of therapeutics. Numerous...
5.
Ostermann N, Ruedisser S, Ehrhardt C, Breitenstein W, Marzinzik A, Jacoby E, et al.
J Med Chem
. 2013 Jan;
56(6):2196-206.
PMID: 23360239
A small library of fragments comprising putative recognition motifs for the catalytic dyad of aspartic proteases was generated by in silico similarity searches within the corporate compound deck based on...
6.
Sutton J, Clark D, Dunsdon S, Fenton G, Fillmore A, Harris N, et al.
Bioorg Med Chem Lett
. 2011 Dec;
22(3):1464-8.
PMID: 22177783
Novel deazaxanthine-based DPP-4 inhibitors have been identified that are potent (IC(50) <10nM) and highly selective versus other dipeptidyl peptidases. Their synthesis and SAR are reported, along with initial efforts to...
7.
Hubschwerlen C, Specklin J, Baeschlin D, Borer Y, Haefeli S, Sigwalt C, et al.
Bioorg Med Chem Lett
. 2003 Nov;
13(23):4229-33.
PMID: 14623007
Oxazolidinone-quinolone hybrids, which combine the pharmacophores of a quinolone and an oxazolidinone, were synthesised and shown to be active against a variety of susceptible and resistant Gram-positive and Gram-negative bacteria....
8.
Baeschlin D, Hyrup B, Benner S, Richert C
J Org Chem
. 1996 Oct;
61(21):7620-7626.
PMID: 11667701
No abstract available.