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Jon M Sutton

Explore the profile of Jon M Sutton including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Namoto K, Sirockin F, Ostermann N, Gessier F, Flohr S, Sedrani R, et al.
Bioorg Med Chem Lett . 2014 Jan; 24(3):731-6. PMID: 24439847
The successful launches of dipeptidyl peptidase IV (DPP IV) inhibitors as oral anti-diabetics warrant and spur the further quest for additional chemical entities in this promising class of therapeutics. Numerous...
2.
Sutton J, Clark D, Dunsdon S, Fenton G, Fillmore A, Harris N, et al.
Bioorg Med Chem Lett . 2011 Dec; 22(3):1464-8. PMID: 22177783
Novel deazaxanthine-based DPP-4 inhibitors have been identified that are potent (IC(50) <10nM) and highly selective versus other dipeptidyl peptidases. Their synthesis and SAR are reported, along with initial efforts to...