Daniel J Nolan
Overview
Explore the profile of Daniel J Nolan including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
3289
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0
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Recent Articles
1.
Lehmann G, Ginsberg M, Nolan D, Rodriguez C, Martinez-Gonzalez J, Zeng S, et al.
Cells
. 2022 Oct;
11(19).
PMID: 36230937
Alpha-2-macroglobulin (A2M) is a protease inhibitor that regulates extracellular matrix (ECM) stability and turnover. Here, we show that A2M is expressed by endothelial cells (ECs) from human eye choroid. We...
2.
Hisata S, Racanelli A, Kermani P, Schreiner R, Houghton S, Palikuqi B, et al.
J Exp Med
. 2021 Jul;
218(8).
PMID: 34287647
Chronic obstructive pulmonary disease (COPD) is marked by airway inflammation and airspace enlargement (emphysema) leading to airflow obstruction and eventual respiratory failure. Microvasculature dysfunction is associated with COPD/emphysema. However, it...
3.
Srivastava S, Truitt L, Wu C, Glaser A, Nolan D, Ginsberg M, et al.
Mol Ther Methods Clin Dev
. 2021 Mar;
20:703-715.
PMID: 33738325
hematopoietic stem and progenitor cell (HSPC) expansion platforms are under active development, designed to increase HSPC numbers and thus engraftment ability of allogeneic cord blood grafts or autologous HSPCs for...
4.
Lehmann G, Hanke-Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, et al.
J Exp Med
. 2020 Mar;
217(6).
PMID: 32196081
The activity and survival of retinal photoreceptors depend on support functions performed by the retinal pigment epithelium (RPE) and on oxygen and nutrients delivered by blood vessels in the underlying...
5.
Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss C, et al.
Sci Immunol
. 2018 Jan;
3(19).
PMID: 29330161
The thymus is not only extremely sensitive to damage but also has a remarkable ability to repair itself. However, the mechanisms underlying this endogenous regeneration remain poorly understood, and this...
6.
Benedicto I, Lehmann G, Ginsberg M, Nolan D, Bareja R, Elemento O, et al.
Nat Commun
. 2017 May;
8:15374.
PMID: 28524846
The outer blood-retina barrier is established through the coordinated terminal maturation of the retinal pigment epithelium (RPE), fenestrated choroid endothelial cells (ECs) and Bruch's membrane, a highly organized basement membrane...
7.
Gori J, Butler J, Kunar B, Poulos M, Ginsberg M, Nolan D, et al.
Stem Cells Transl Med
. 2017 Mar;
6(3):864-876.
PMID: 28297579
Successful expansion of bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs) would benefit many HSPC transplantation and gene therapy/editing applications. However, current expansion technologies have been limited by a...
8.
Gori J, Butler J, Chan Y, Chandrasekaran D, Poulos M, Ginsberg M, et al.
J Clin Invest
. 2015 Feb;
125(3):1243-54.
PMID: 25664855
Pluripotent stem cells (PSCs) represent an alternative hematopoietic stem cell (HSC) source for treating hematopoietic disease. The limited engraftment of human PSC-derived (hPSC-derived) multipotent progenitor cells (MPP) has hampered the...
9.
Ding B, Cao Z, Lis R, Nolan D, Guo P, Simons M, et al.
Nature
. 2013 Nov;
505(7481):97-102.
PMID: 24256728
Chemical or traumatic damage to the liver is frequently associated with aberrant healing (fibrosis) that overrides liver regeneration. The mechanism by which hepatic niche cells differentially modulate regeneration and fibrosis...
10.
Nolan D, Ginsberg M, Israely E, Palikuqi B, Poulos M, James D, et al.
Dev Cell
. 2013 Jul;
26(2):204-19.
PMID: 23871589
Microvascular endothelial cells (ECs) within different tissues are endowed with distinct but as yet unrecognized structural, phenotypic, and functional attributes. We devised EC purification, cultivation, profiling, and transplantation models that...