Daniel Gamu
Overview
Explore the profile of Daniel Gamu including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
317
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Recent Articles
1.
Gibson W, Lengyell T, Korecki A, Janssen S, Adair B, Gamu D, et al.
Hum Gene Ther
. 2025 Feb;
36(5-6):618-627.
PMID: 39964768
Weaver syndrome is a rare neurodevelopmental disorder that encompasses macrocephaly, tall stature, obesity, brain anomalies, intellectual disability, and increased susceptibility to cancer. This dominant monogenic disorder is caused by germline...
2.
Gamu D, Cameron M, Gibson W
Am J Physiol Endocrinol Metab
. 2024 Aug;
327(4):E459-E468.
PMID: 39140972
Brown and beige adipose tissues are specialized for thermogenesis and are important for energy balance in mice. Mounting evidence suggests that chromatin-modifying enzymes are integral for the development, maintenance, and...
3.
Kajabadi N, Low M, Jacques E, Lad H, Tung L, Babaeijandaghi F, et al.
Dev Cell
. 2023 Mar;
58(6):489-505.e7.
PMID: 36898377
Loss of muscle mass is a common manifestation of chronic disease. We find the canonical Wnt pathway to be activated in mesenchymal progenitors (MPs) from cancer-induced cachectic mouse muscle. Next,...
4.
5.
Gamu D, Gibson W
J Clin Endocrinol Metab
. 2021 Apr;
106(8):e3266-e3268.
PMID: 33860317
No abstract available.
6.
Fu M, Bombardier E, Gamu D, Tupling A
Biochem J
. 2020 Oct;
477(21):4281-4294.
PMID: 33111944
Na+-K+-ATPase from mice lacking the γ subunit exhibits decreased thermal stability. Phospholamban (PLN) and sarcolipin (SLN) are small homologous proteins that regulate sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) with properties similar to...
7.
Gamu D, Gibson W
Cold Spring Harb Mol Case Stud
. 2020 Aug;
6(4).
PMID: 32843427
Within histone H3, lysine 27 (H3K27) is one of the residues that functions as a molecular switch, by virtue of being subject to mutually exclusive post-translational modifications that have reciprocal...
8.
Gamu D, Juracic E, Hall K, Tupling A
Appl Physiol Nutr Metab
. 2019 May;
45(1):1-10.
PMID: 31116956
We are currently facing an "obesity epidemic" worldwide. Promoting inefficient metabolism in muscle represents a potential treatment for obesity and its complications. Sarco(endo)plasmic reticulum (SR) Ca-ATPase (SERCA) pumps in muscle...
9.
Gamu D, Juracic E, Fajardo V, Rietze B, Tran K, Bombardier E, et al.
Am J Physiol Endocrinol Metab
. 2019 Jan;
316(3):E432-E442.
PMID: 30601702
The sarco(endo)plasmic reticulum Ca-ATPase (SERCA) pump is a major contributor to skeletal muscle Ca homeostasis and metabolic rate. SERCA activity can become adaptively uncoupled by its regulator sarcolipin (SLN) to...
10.
Fajardo V, Chambers P, Juracic E, Rietze B, Gamu D, Bellissimo C, et al.
Hum Mol Genet
. 2018 Aug;
27(23):4094-4102.
PMID: 30137316
Duchenne muscular dystrophy (DMD) is the most severe form of muscular dystrophy affecting 1 in 3500 live male births. Although there is no cure for DMD, therapeutic strategies aimed at...