Daniel E Goldberg
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Explore the profile of Daniel E Goldberg including associated specialties, affiliations and a list of published articles.
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126
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3614
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Recent Articles
11.
Huang L, Jasim I, Alkorjia O, Agca C, Oksman A, Agca Y, et al.
Anal Chim Acta
. 2023 May;
1267:341226.
PMID: 37257960
-In this paper, we investigate a microfluidic based sensing device for cell membrane permeability measurements in real time with applications in rapid assessment of red blood cell (RBC) quality at...
12.
Mukherjee S, Nasamu A, Rubiano K, Goldberg D
mBio
. 2023 Apr;
14(2):e0067323.
PMID: 37036362
Following each round of replication, daughter merozoites of the malaria parasite Plasmodium falciparum escape (egress) from the infected host red blood cell (RBC) by rupturing the parasitophorous vacuole membrane (PVM)...
13.
Bohmer M, Wang J, Istvan E, Luth M, Collins J, Huttlin E, et al.
ACS Infect Dis
. 2023 Mar;
9(4):1004-1021.
PMID: 36919909
Protein kinases have proven to be a very productive class of therapeutic targets, and over 90 inhibitors are currently in clinical use primarily for the treatment of cancer. Repurposing these...
14.
Istvan E, Guerra F, Abraham M, Huang K, Rocamora F, Zhao H, et al.
Sci Transl Med
. 2023 Mar;
15(686):eadc9249.
PMID: 36888694
Development of antimalarial compounds into clinical candidates remains costly and arduous without detailed knowledge of the target. As resistance increases and treatment options at various stages of disease are limited,...
15.
Polino A, Hasan M, Floyd K, Avila-Cruz Y, Yang Y, Goldberg D
J Cell Sci
. 2023 Feb;
136(6).
PMID: 36744402
N-terminal acetylation is a common eukaryotic protein modification that involves the addition of an acetyl group to the N-terminus of a polypeptide. This modification is largely performed by cytosolic N-terminal...
16.
Mukherjee S, Nasamu A, Rubiano K, Goldberg D
bioRxiv
. 2023 Jan;
PMID: 36712005
Significance Statement: Malaria parasites replicate inside a parasitophorous vacuole within the host red blood cells. Exit of mature progeny from the infected host cells is essential for further dissemination. Parasite...
17.
Lowe M, Cardenas A, Valentin J, Zhu Z, Abendroth J, Castro J, et al.
J Med Chem
. 2022 Oct;
65(20):14121-14143.
PMID: 36216349
Plasmepsin X (PMX) is an essential aspartyl protease controlling malaria parasite egress and invasion of erythrocytes, development of functional liver merozoites (prophylactic activity), and blocking transmission to mosquitoes, making it...
18.
Polino A, Miller J, Bhakat S, Mukherjee S, Bobba S, Bowman G, et al.
J Biol Chem
. 2022 Aug;
298(9):102355.
PMID: 35952758
Plasmepsin V (PM V) is a pepsin-like aspartic protease essential for growth of the malarial parasite Plasmodium falciparum. Previous work has shown PM V to be an endoplasmic reticulum-resident protease...
19.
Mukherjee S, Nguyen S, Sharma E, Goldberg D
Nat Commun
. 2022 Aug;
13(1):4537.
PMID: 35927261
The malaria parasite Plasmodium invades a host erythrocyte, multiplies within a parasitophorous vacuole (PV) and then ruptures the PV and erythrocyte membranes in a process known as egress. Both egress...
20.
Dvorin J, Goldberg D
Annu Rev Microbiol
. 2022 Apr;
76:67-90.
PMID: 35417197
Human malaria, caused by infection with parasites, remains one of the most important global public health problems, with the World Health Organization reporting more than 240 million cases and 600,000...