Daniel C Berwick
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Explore the profile of Daniel C Berwick including associated specialties, affiliations and a list of published articles.
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18
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734
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Recent Articles
11.
Berwick D, Harvey K
Biochem Soc Trans
. 2012 Sep;
40(5):1123-8.
PMID: 22988876
PD (Parkinson's disease) is a devastating progressive motor disorder with no available cure. Over the last two decades, an increasing number of genetic defects have been found that cause familial...
12.
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
Berwick D, Harvey K
Hum Mol Genet
. 2012 Aug;
21(22):4966-79.
PMID: 22899650
Mutations in PARK8, encoding leucine-rich repeat kinase 2 (LRRK2), are a frequent cause of Parkinson's disease (PD). Nonetheless, the physiological role of LRRK2 remains unclear. Here, we demonstrate that LRRK2...
13.
Berwick D, Harvey K
Trends Cell Biol
. 2011 Feb;
21(5):257-65.
PMID: 21306901
Mutations in PARK8, encoding leucine-rich repeat kinase 2 (LRRK2), are a major cause of Parkinson's disease. We contrast data suggesting that changes in LRRK2 activity cause alterations in mitogen-activated protein...
14.
Berwick D, Diss J, Budhram-Mahadeo V, Latchman D
J Biol Chem
. 2010 Mar;
285(20):15286-15295.
PMID: 20228055
The formation of multiprotein complexes constitutes a key step in determining the function of any translated gene product. Thus, the elucidation of interacting partners for a protein of interest is...
15.
Berwick D, Calissano M, Corness J, Cook S, Latchman D
Brain Res
. 2009 Jan;
1256:8-18.
PMID: 19135033
The POU family transcription factor Brn-3a is required for the differentiation and survival of sensory neurones, and is phosphorylated in neuroblastoma cells following treatment with all-trans retinoic acid (RA). Mutation...
16.
Berwick D, Dell G, Welsh G, Heesom K, Hers I, Fletcher L, et al.
J Cell Sci
. 2004 Nov;
117(Pt 25):5985-93.
PMID: 15546921
Insulin-stimulated glucose uptake involves the recruitment of the glucose transporter 4 isoform (GLUT4) from an intracellular location to the plasma membrane of fat and muscle cells. Although the activation of...
17.
Berwick D, Tavare J
Trends Biochem Sci
. 2004 May;
29(5):227-32.
PMID: 15130558
No abstract available.
18.
Berwick D, Hers I, Heesom K, Moule S, Tavare J
J Biol Chem
. 2002 Jul;
277(37):33895-900.
PMID: 12107176
Protein kinase B (Akt) plays a central role in cellular regulation, although many of the physiologically relevant substrates for the kinase remain to be identified. In this study, we have...