Daniel B McKim
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Explore the profile of Daniel B McKim including associated specialties, affiliations and a list of published articles.
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31
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1366
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Recent Articles
1.
Auger S, Pedersen J, Maity S, Sprague-Getsy A, Lorimer E, Koehn O, et al.
Biochemistry
. 2024 Dec;
64(1):138-155.
PMID: 39652878
Prenylation consists of the modification of proteins with either farnesyl diphosphate (FPP) or geranylgeranyl diphosphate (GGPP) at a cysteine near the C-terminus of target proteins to generate thioether-linked lipidated proteins....
2.
Nemeth D, Liu X, Monet M, Niu H, Maxey G, Schrier M, et al.
J Neuroinflammation
. 2024 Nov;
21(1):303.
PMID: 39563437
Interleukin-1 (IL-1) is a pro-inflammatory cytokine that exerts a wide range of neurological and immunological effects throughout the central nervous system (CNS) and is associated with the etiology of affective...
3.
Sawicki C, McKim D, Wang H, Vasas M, Blakeslee J, Jatana C, et al.
Anesth Prog
. 2024 Nov;
71(3):109-114.
PMID: 39503141
Objective: Dilution of concentrated epinephrine prior to intravenous use during clinical emergencies can delay urgent interventions. The objective of this study was to determine whether diluted epinephrine remains stable and...
4.
Krauklis S, Hussain J, Murphy K, Dray E, Ousley C, Justyna K, et al.
Am J Physiol Endocrinol Metab
. 2024 May;
327(1):E55-E68.
PMID: 38717364
Statins are used to treat hypercholesterolemia and function by inhibiting the production of the rate-limiting metabolite mevalonate. As such, statin treatment not only inhibits de novo synthesis of cholesterol but...
5.
Louie A, Kim J, Drnevich J, Dibaeinia P, Koito H, Sinha S, et al.
J Neuroinflammation
. 2023 Aug;
20(1):190.
PMID: 37596606
Background: Recent data suggest that myelin may be altered by physiological events occurring outside of the central nervous system, which may cause changes to cognition and behavior. Similarly, peripheral infection...
6.
Hussain J, Ousley C, Krauklis S, Dray E, Drnevich J, McKim D
Immunobiology
. 2023 Jun;
228(4):152411.
PMID: 37329824
Cross sectional studies have shown that statin-users have improved odds of surviving severe sepsis. Meanwhile controlled clinical trials failed to demonstrate improved sepsis survival with acute statin administration following hospitalization....
7.
Louie A, Tingling J, Dray E, Hussain J, McKim D, Swanson K, et al.
J Immunol
. 2022 May;
208(11):2523-2539.
PMID: 35577367
Influenza is a common cause of pneumonia-induced hospitalization and death, but how host factors function to influence disease susceptibility or severity has not been fully elucidated. Cellular cholesterol levels may...
8.
Nemeth D, Liu X, McKim D, DiSabato D, Oliver B, Herd A, et al.
J Inflamm Res
. 2022 Mar;
15:1575-1590.
PMID: 35282272
Introduction: Lipopolysaccharide (LPS) preconditioning involves repeated, systemic, and sub-threshold doses of LPS, which induces a neuroprotective state within the CNS, thus preventing neuronal death and functional losses. Recently, proinflammatory cytokine,...
9.
Soto-Diaz K, Vailati-Riboni M, Louie A, McKim D, Gaskins H, Johnson R, et al.
Front Immunol
. 2021 Dec;
12:734349.
PMID: 34899694
Microglia activation and proliferation are hallmarks of many neurodegenerative disorders and may contribute to disease pathogenesis. Neurons actively regulate microglia survival and function, in part by secreting the microglia mitogen...
10.
Witcher K, Bray C, Chunchai T, Zhao F, ONeil S, Gordillo A, et al.
J Neurosci
. 2021 Jan;
41(7):1597-1616.
PMID: 33452227
Traumatic brain injury (TBI) can lead to significant neuropsychiatric problems and neurodegenerative pathologies, which develop and persist years after injury. Neuroinflammatory processes evolve over this same period. Therefore, we aimed...