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Daniel B McKim

Explore the profile of Daniel B McKim including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 1366
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Recent Articles
11.
Dray E, Ousley C, McKim D
Mol Immunol . 2021 Jan; 131:127-136. PMID: 33441247
Stromal cells are critical regulators of bone marrow hematopoietic niches, but assessment of their regulatory roles has been impeded by difficult and ineffective dissociation methods. Here, we methodically address bone...
12.
Zhu L, Liu X, Nemeth D, DiSabato D, Witcher K, McKim D, et al.
Brain Behav Immun . 2019 Jun; 81:292-304. PMID: 31228609
As a major producer of the inflammatory cytokine interleukin-1 (IL-1), peripheral macrophages can augment IL-1 expression via type 1 IL-1 receptor (IL-1R1) mediated autocrine self-amplification. In the CNS, microglial cells...
13.
Sullivan K, Bever S, McKim D, Godbout J, Sheridan J, Obrietan K, et al.
Brain Behav Immun . 2019 May; 80:805-817. PMID: 31108169
Circadian rhythms influence various aspects of biology, including hormonal, immunological, and behavioral processes. These 24-hour oscillations are necessary to optimize cellular functions and to synchronize these processes with the environment....
14.
Liu X, Nemeth D, McKim D, Zhu L, DiSabato D, Berdysz O, et al.
Immunity . 2019 Mar; 50(3):764-766. PMID: 30893590
No abstract available.
15.
Yin W, Gallagher N, Sawicki C, McKim D, Godbout J, Sheridan J
Brain Behav Immun . 2019 Jan; 78:131-142. PMID: 30684650
Anxiety and mood disorders affect both men and women. The majority of experimental models of stress, however, are completed using only male animals. For repeated social defeat (RSD), a rodent...
16.
Liu X, Nemeth D, McKim D, Zhu L, DiSabato D, Berdysz O, et al.
Immunity . 2019 Jan; 50(2):317-333.e6. PMID: 30683620
Interleukin-1 (IL-1) signaling is important for multiple potentially pathogenic processes in the central nervous system (CNS), but the cell-type-specific roles of IL-1 signaling are unclear. We used a genetic knockin...
17.
Sawicki C, Kim J, Weber M, Faw T, McKim D, Madalena K, et al.
J Neurosci . 2018 Dec; 39(7):1139-1149. PMID: 30559153
Clinical studies indicate that psychosocial stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Repeated social defeat (RSD)...
18.
Weber M, McKim D, Niraula A, Witcher K, Yin W, Sobol C, et al.
Biol Psychiatry . 2018 Dec; 85(8):667-678. PMID: 30527629
Background: Stress is associated with an increased prevalence of anxiety and depression. Repeated social defeat (RSD) stress in mice increases the release of monocytes from the bone marrow that are...
19.
McKim D, Yin W, Wang Y, Cole S, Godbout J, Sheridan J
Cell Rep . 2018 Nov; 25(9):2552-2562.e3. PMID: 30485819
Psychosocial stress accelerates myelopoietic production of monocytes and neutrophils that contributes to a variety of health complications ranging from atherosclerosis to anxiety. Here, we show that social stress in mice...
20.
ONeil S, Witcher K, McKim D, Godbout J
Acta Neuropathol Commun . 2018 Nov; 6(1):129. PMID: 30477578
Microglia are the resident innate immune cells of the central nervous system. Limited turnover throughout the lifespan leaves microglia susceptible to age-associated dysfunction. Indeed, we and others have reported microglia...