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Daishiro Miura

Explore the profile of Daishiro Miura including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 167
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Recent Articles
1.
Tasaki D, Tsuruda K, Sun S, Tsumura Y, Asano S, Suzuki Y, et al.
Rheumatology (Oxford) . 2024 Jul; 64(3):1036-1044. PMID: 39002122
Objective: The purpose of this study was to evaluate the safety, tolerability, pharmacokinetics and efficacy (as an exploratory endpoint) of TCK-276, a novel CDK4/6 inhibitor, after multiple oral doses for...
2.
Dertinger S, Bhalli J, Roberts D, Stankowski Jr L, Gollapudi B, Lovell D, et al.
Environ Mol Mutagen . 2021 Feb; 62(3):227-237. PMID: 33608913
The rodent Pig-a assay is a flow cytometric, phenotype-based method used to measure in vivo somatic cell mutation. An Organization for Economic Co-operation and Development (OECD) test guideline is currently...
3.
Dobrovolsky V, Shaddock J, Mittelstaedt R, Miura D, Heflich R
Methods Mol Biol . 2019 Sep; 2031:59-75. PMID: 31473954
Assays for in vivo mutation are used to identify genotoxic hazards and phenotypes prone to genomic instability and cancer. The hypoxanthine guanine phosphoribosyl transferase (Hprt) gene and the phosphatidyl inositol...
4.
Iwata M, Yamamoto W, Shimomoto T, Okada Y, Oosawa S, Miura D, et al.
J Toxicol Pathol . 2018 May; 31(2):151-154. PMID: 29750005
Growth plates at each end of vertebral bodies play a pivotal role in longitudinal spinal growth. Epiphyseal closures are formed in adult humans. Although monkeys are frequently employed in bone...
5.
Kimoto T, Miura D
Methods Mol Biol . 2017 Jul; 1641:161-172. PMID: 28748463
Detection of in vivo mutation is important for evaluating the health risks associated with chemicals. The Pig-a in vivo gene mutation assay has been developed over the last decade for...
6.
Kimoto T, Horibata K, Miura D, Chikura S, Okada Y, Ukai A, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2016 Dec; 811:3-15. PMID: 27931811
The in vivo mutation assay using the X-linked phosphatidylinositol glycan class A gene (Pig-a in rodents, PIG-A in humans) is a promising tool for evaluating the mutagenicity of chemicals. Approaches...
7.
Chikura S, Okada Y, Kimoto T, Kaneko H, Miura D, Kasahara Y
Mutat Res Genet Toxicol Environ Mutagen . 2016 Dec; 811:21-28. PMID: 27931809
As part of a collaborative study in the Mammalian Mutagenicity Study (MMS) Group of the Japanese Environmental Mutagen Society (JEMS), we investigated the in vivo genotoxicity profile of 1,2-dimethylhydrazine (DMH)...
8.
Chikura S, Okada Y, Kimoto T, Kaneko H, Miura D, Kasahara Y
Mutat Res Genet Toxicol Environ Mutagen . 2016 Dec; 811:110-116. PMID: 27931803
As part of a collaborative study in the Mammalian Mutagenicity Study group of the Japanese Environmental Mutagen Society, we evaluated the in vivo mutagenicity of isopropyl p-toluenesulfonate (IPTS) using a...
9.
Kobayashi T, Namekawa J, Shimomoto T, Yasui M, Iijima T, Itano Y, et al.
J Toxicol Sci . 2015 Nov; 40(6):719-25. PMID: 26558452
Glucose has an important role in spermatogenesis. Nevertheless there are few reports in which the effects of long-lasting hypoglycemia on male reproductive organs have been evaluated. Therefore, insulin was administered...
10.
Yamamoto W, Itano Y, Kobayashi T, Miura D, Kasahara Y
J Vet Med Sci . 2015 Sep; 78(1):77-82. PMID: 26321444
Human immunoglobulin G (IgG) concentrates are immune-modulating, anti-inflammatory plasma-derived products. Clinical studies in recent years have suggested that IgG attenuates neuropathic pain. In this study, effects of sulphonated IgG on...