D R Petersen
Overview
Explore the profile of D R Petersen including associated specialties, affiliations and a list of published articles.
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Articles
79
Citations
843
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Recent Articles
1.
Luckey S, Petersen D
Exp Mol Pathol
. 2001 Dec;
71(3):226-40.
PMID: 11733948
Kupffer cells are involved in the pathogenesis of chemically mediated liver injury through release of biologically active mediators that promote the pathogenic process. The purpose of this study was to...
2.
Luckey S, Petersen D
Arch Biochem Biophys
. 2001 May;
389(1):77-83.
PMID: 11370675
Kupffer cells are known to participate in the early events of liver injury involving lipid peroxidation. 4-Hydroxy-2,3-(E)-nonenal (4-HNE), a major aldehydic product of lipid peroxidation, has been shown to modulate...
3.
Vasiliou V, Pappa A, Petersen D
Chem Biol Interact
. 2001 Jan;
129(1-2):1-19.
PMID: 11154732
Aldehydes are highly reactive molecules that are intermediates or products involved in a broad spectrum of physiologic, biologic and pharmacologic processes. Aldehydes are generated from chemically diverse endogenous and exogenous...
4.
Reichard J, Vasiliou V, Petersen D
Biochim Biophys Acta
. 2000 Oct;
1487(2-3):222-32.
PMID: 11018474
During oxidative stress, reactive aldehydes, including trans-4-hydroxy-2-nonenal (4-HNE), are generated by peroxidation of membrane lipids and purportedly stimulate hepatic stellate cells to produce excessive extracellular matrix, including type I collagen....
5.
Vasiliou V, Lee J, Pappa A, Petersen D
Biochem Biophys Res Commun
. 2000 Jun;
273(2):546-50.
PMID: 10873642
We have examined the NF-kappaB binding and functional activities in two stellate cell lines derived from normal (NFSC) and cirrhotic (CFSC) rat liver. Gel mobility shift assays revealed two bands...
6.
Chen J, Petersen D, Schenker S, Henderson G
Alcohol Clin Exp Res
. 2000 May;
24(4):544-52.
PMID: 10798592
Background: Previous studies in our laboratory demonstrated that short-term ethanol consumption by maternal rats increased the hepatic levels of 4-hydroxynonenal (HNE) in both the adult and the fetus. Additionally, HNE...
7.
Valerio Jr L, Petersen D
Exp Mol Pathol
. 2000 Jan;
68(1):1-12.
PMID: 10640449
A unique organic form of iron (dicyclopentadienyl iron; ferrocene) has been used to further elucidate specific hepatic histopathologic, biochemical, and molecular parameters associated with dietary iron overload. Male C57BL/6Ibg mice...
8.
Hartley D, Kolaja K, REICHARD J, Petersen D
Toxicol Appl Pharmacol
. 1999 Nov;
161(1):23-33.
PMID: 10558920
The metabolism of CCl(4) initiates the peroxidation of polyunsaturated fatty acids producing alpha,beta-unsaturated aldehydes, such as 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA). The facile reactivity of these electrophilic aldehydic products suggests...
9.
Tjalkens R, Luckey S, Kroll D, Petersen D
Adv Exp Med Biol
. 1999 Jun;
463:123-31.
PMID: 10352677
No abstract available.
10.
Luckey S, Tjalkens R, Petersen D
Adv Exp Med Biol
. 1999 Jun;
463:71-7.
PMID: 10352671
No abstract available.