D Y Mitchell
Overview
Explore the profile of D Y Mitchell including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
152
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Recent Articles
1.
Mitchell D, Barr W, Eusebio R, STEVENS K, Duke F, Russell D, et al.
Pharm Res
. 2001 Jun;
18(2):166-70.
PMID: 11405286
Purpose: To determine the pharmacokinetics and absolute bioavailability of risedronate after single-dose oral administration of 30 mg risedronate as a tablet and an aqueous solution, and 0.3 mg risedronate as...
2.
Mitchell D, St Peter J, Eusebio R, Pallone K, Kelly S, Russell D, et al.
Br J Clin Pharmacol
. 2000 Mar;
49(3):215-22.
PMID: 10718776
Aims: To determine the relationship between risedronate pharmacokinetics and renal function. Methods: Risedronate was administered to adult men and women (n=21) with various degrees of renal function (creatinine clearance 15-126...
3.
Mitchell D, Eusebio R, Pallone K, Kelly S, Nesbitt J, Brezovic C, et al.
J Clin Pharmacol
. 2000 Mar;
40(3):258-65.
PMID: 10709154
Risedronate is a pyridinyl bisphosphonate approved for the treatment of Paget's disease (US-FDA) and in development for the treatment and prevention of osteoporosis. This study examined risedronate pharmacokinetics and tolerability...
4.
Mitchell D, Heise M, Pallone K, Clay M, Nesbitt J, Russell D, et al.
Br J Clin Pharmacol
. 1999 Dec;
48(4):536-42.
PMID: 10583024
Aims: To examine the effect of timing of a risedronate dose relative to food intake on the rate and extent of risedronate absorption following single-dose, oral administration to healthy male...
5.
Mitchell D, Eusebio R, Dunlap L, Pallone K, Nesbitt J, Russell D, et al.
Pharm Res
. 1998 Apr;
15(2):228-32.
PMID: 9523308
Purpose: Two studies were conducted to compare the absorption of risedronate administered as a solution to three different gastrointestinal sites (study A) and to determine the extent of absorption of...
6.
Robinson R, Reiter L, Barth W, Campeta A, Cooper K, Cronin B, et al.
J Med Chem
. 1996 Jan;
39(1):10-8.
PMID: 8568796
Ether, ester, and carbonate derivatives of the antirheumatic oxindole 1 were prepared and screened as potential prodrugs of 1. This effort led to the discovery of the (alpha-L-alanyloxy)-methyl ether and...
7.
Mitchell D, Petersen D
Drug Metab Dispos
. 1993 Mar;
21(2):396-9.
PMID: 8097715
No abstract available.
8.
Madhu C, Mitchell D, Klaassen C
Drug Metab Dispos
. 1993 Mar;
21(2):342-9.
PMID: 8097707
This study was designed to determine if a relationship exists between hepatic gamma-glutamyltranspeptidase (gamma-GT) activity and the biliary excretion of glutathione (GSH) and its hydrolysis products. Rats were pretreated with...
9.
Avery M, Mitchell D, Falkner F, Fouda H
Biol Mass Spectrom
. 1992 Jul;
21(7):353-7.
PMID: 1420376
A specific high-performance liquid chromatographic/atmospheric pressure chemical ionization tandem mass spectrometric assay for the quantitative determination of tenidap and its D3 analog in human serum is described. The assay exhibited...
10.
Mitchell D, Petersen D
Hepatology
. 1991 Apr;
13(4):728-34.
PMID: 2010168
The hepatic oxidation of ethanol has been demonstrated to cause peroxidation of cellular membranes, resulting in the production of aldehydes that are substrates for hepatic aldehyde dehydrogenases. It was the...