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D Hicklin

Explore the profile of D Hicklin including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 1091
Followers 0
Related Specialties
General Medicine
Biochemistry
Oncology
Top 10 Co-Authors
L Witte
I R Lemischka
S Rafii
S Dias
K Hattori
H Waksal
S Jothy
L Butros
T Cohen
S Dagan
Published In
J Pers Soc Psychol
J Biol Chem
Cancer Res
Lab Invest
Proc Natl Acad Sci U S A
Affiliations
Soon will be listed here.
Recent Articles
1.
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, et al.
Nat Med . 2001 Nov; 7(11):1194-201. PMID: 11689883
The role of bone marrow (BM)-derived precursor cells in tumor angiogenesis is not known. We demonstrate here that tumor angiogenesis is associated with recruitment of hematopoietic and circulating endothelial precursor...
2.
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis
Viloria-Petit A, Crombet T, Jothy S, Hicklin D, Bohlen P, Schlaeppi J, et al.
Cancer Res . 2001 Jun; 61(13):5090-101. PMID: 11431346
Inhibitors of epidermal growth factor receptor (EGFR) signaling are among the novel drugs showing great promise for cancer treatment in the clinic. However, the possibility of acquired resistance to such...
3.
Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells
Gill M, Dias S, Hattori K, Rivera M, Hicklin D, Witte L, et al.
Circ Res . 2001 Feb; 88(2):167-74. PMID: 11157668
Bone marrow (BM)-derived circulating endothelial precursor cells (CEPs) are thought to play a role in postnatal angiogenesis. Emerging evidence suggests that angiogenic stress of vascular trauma may induce mobilization of...
4.
Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs
Moore K, Pytowski B, Witte L, Hicklin D, Lemischka I
Proc Natl Acad Sci U S A . 1997 Apr; 94(8):4011-6. PMID: 9108096
Primitive hematopoietic stem cells are closely associated with discrete in vivo microenvironments. These "niches" are thought to provide the molecular signals that mediate stem cell differentiation and self-renewal. We have...
5.
High-level expression of a biologically active human interleukin-6 mutein
Skelly S, Tackney C, Hicklin D, Tamkins T, Goldstein N, Waksal H, et al.
J Biotechnol . 1994 Apr; 34(1):79-86. PMID: 7764745
We have constructed two different muteins of interleukin-6 (IL-6) which were expressed in Escherichia coli. Both muteins lack the first 22 N-terminal amino acids of native IL-6 and lack one...
6.
Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors
Tessler S, Rockwell P, Hicklin D, Cohen T, Levi B, Witte L, et al.
J Biol Chem . 1994 Apr; 269(17):12456-61. PMID: 8175651
The 165-amino acid form of vascular endothelial growth factor (VEGF165) is a mitogen for vascular endothelial cells and a potent angiogenic factor. Expression of a chimeric receptor containing the extracellular...
7.
Expression of basic fibroblast growth factor in normal human tissues
Cordon-Cardo C, Vlodavsky I, Haimovitz-Friedman A, Hicklin D, Fuks Z
Lab Invest . 1990 Dec; 63(6):832-40. PMID: 2255190
The distribution of basic fibroblast growth factor (bFGF) was studied immunohistochemically in fresh frozen sections of normal human tissues. Immunodetection was performed with a specific anti-bFGF mouse monoclonal antibody that...
8.
Social support and immune function among spouses of cancer patients
Baron R, Cutrona C, Hicklin D, Russell D, Lubaroff D
J Pers Soc Psychol . 1990 Aug; 59(2):344-52. PMID: 2213497
This study investigated whether social support was related to immune function among spouses of cancer patients. Effects of depression and negative life events were examined as potential mediators. Results showed...