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D Constantin-Teodosiu

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Articles 40
Citations 946
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Recent Articles
1.
Farrash W, Brook M, Crossland H, Phillips B, Cegielski J, Wilkinson D, et al.
Am J Physiol Endocrinol Metab . 2020 May; 318(6):E943-E955. PMID: 32369414
Myokines, such as irisin, have been purported to exert physiological effects on skeletal muscle in an autocrine/paracrine fashion. In this study, we aimed to investigate the mechanistic role of in...
2.
Constantin-Teodosiu D, Cederblad G, Bergstrom M, Greenhaff P
Clin Nutr . 2018 Feb; 38(2):948-953. PMID: 29459213
Background & Aims: Exercise activates muscle pyruvate dehydrogenase complex (PDC), but moderate intensity exercise fails to fully activate muscle PDC after high-fat diet [1]. We investigated whether maximal intensity exercise...
3.
Vigelso A, Gram M, Dybboe R, Kuhlman A, Prats C, Greenhaff P, et al.
J Physiol . 2016 Jan; 594(8):2339-58. PMID: 26801521
Key Points: This study aimed to provide molecular insight into the differential effects of age and physical inactivity on the regulation of substrate metabolism during moderate-intensity exercise. Using the arteriovenous...
4.
Alamdari N, Constantin-Teodosiu D, Murton A, Gardiner S, Bennett T, Layfield R, et al.
J Physiol . 2008 Jan; 586(6):1767-75. PMID: 18218678
A characteristic manifestation of sepsis is muscle lactate accumulation. This study examined any putative (causative) association between pyruvate dehydrogenase complex (PDC) inhibition and lactate accumulation in the extensor digitorum longus...
5.
Baker D, Constantin-Teodosiu D, Jones S, Timmons J, Greenhaff P
J Pharmacol Exp Ther . 2006 Jul; 319(1):439-46. PMID: 16844843
Discovering approaches to maintain or improve muscle function (fatigue resistance) in patients with cachexia, postoperative weakness, and sarcopenia is of clinical importance. beta(2)-Agonist treatment increases muscle mass, yet it alters...
6.
Greenhaff P, Campbell-OSullivan S, Constantin-Teodosiu D, Poucher S, Roberts P, Timmons J
Br J Clin Pharmacol . 2004 Mar; 57(3):237-43. PMID: 14998419
Peripheral vascular disease (PVD) is generally accepted to result in the failure of skeletal muscle blood flow to increase adequately at the onset of muscular work. There are currently no...
7.
Greenhaff P, Campbell-OSullivan S, Constantin-Teodosiu D, Poucher S, Roberts P, Timmons J
Biochem Soc Trans . 2002 May; 30(2):275-80. PMID: 12023864
The oxygen deficit at the onset of submaximal exercise represents a period when the energy demand of contraction cannot be met solely by mitochondrial ATP generation, and as a consequence...
8.
Tsintzas K, Williams C, Constantin-Teodosiu D, Hultman E, Boobis L, Clarys P, et al.
J Physiol . 2001 Nov; 537(Pt 1):305-11. PMID: 11711582
1. The aim of this study was to examine the effect of carbohydrate (CHO) ingestion on changes in ATP and phosphocreatine (PCr) concentrations in different muscle fibre types during prolonged...
9.
van Loon L, Greenhaff P, Constantin-Teodosiu D, Saris W, Wagenmakers A
J Physiol . 2001 Oct; 536(Pt 1):295-304. PMID: 11579177
1. Contemporary stable isotope methodology was applied in combination with muscle biopsy sampling to accurately quantify substrate utilisation and study the regulation of muscle fuel selection during exercise. 2. Eight...
10.
Bruce M, Constantin-Teodosiu D, Greenhaff P, Boobis L, Williams C, Bowtell J
Am J Physiol Endocrinol Metab . 2001 Mar; 280(4):E669-75. PMID: 11254475
The aims of the present study were twofold: first to investigate whether TCA cycle intermediate (TCAI) pool expansion at the onset of moderate-intensity exercise in human skeletal muscle could be...