D Constantin-Teodosiu
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Explore the profile of D Constantin-Teodosiu including associated specialties, affiliations and a list of published articles.
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946
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Recent Articles
11.
Tsintzas K, Williams C, Constantin-Teodosiu D, Hultman E, Boobis L, Greenhaff P
Exp Physiol
. 2000 Oct;
85(5):581-6.
PMID: 11038410
This study examined the effect of pre-exercise carbohydrate (CHO) ingestion on pyruvate dehydrogenase complex (PDC) activation, acetyl group availability and substrate level phosphorylation (glycogenolysis and phosphocreatine (PCr) hydrolysis) in human...
12.
The tricarboxylic acid cycle in human skeletal muscle: is there a role for nutritional intervention?
Constantin-Teodosiu D, Greenhaff P
Curr Opin Clin Nutr Metab Care
. 2000 Mar;
2(6):527-31.
PMID: 10678684
The tricarboxylic acid (TCA) cycle is essential for oxidative energy production. The expansion (anaplerosis) of the intermediates of the TCA cycle is achieved via a number of pathways, and is...
13.
Constantin-Teodosiu D, Simpson E, Greenhaff P
Am J Physiol
. 1999 Mar;
276(3):E472-8.
PMID: 10070012
No studies have singularly investigated the relationship between pyruvate availability, pyruvate dehydrogenase complex (PDC) activation, and anaplerosis in skeletal muscle. This is surprising given the functional importance attributed to these...
14.
Randall M, Keon C, Greenhaff P, Constantin-Teodosiu D
Br J Pharmacol
. 1998 Jun;
124(1):245-51.
PMID: 9630366
1. Ischaemic cardiac preconditioning represents an important cardioprotective mechanism which limits myocardial ischaemic damage. The aim of this investigation was to assess the impact of dichloroacetate (DCA), a pyruvate dehydrogenase...
15.
Timmons J, Poucher S, Constantin-Teodosiu D, MacDonald I, Greenhaff P
Am J Physiol
. 1998 Jun;
274(5):R1384-9.
PMID: 9612406
Pyruvate dehydrogenase complex (PDC) activation status has been described as being central in the regulation of tissue substrate oxidation as outlined by the glucose fatty-acid cycle. In the present study...
16.
Timmons J, Gustafsson T, Sundberg C, Jansson E, Hultman E, Kaijser L, et al.
J Clin Invest
. 1998 Feb;
101(1):79-85.
PMID: 9421469
We have demonstrated previously that dichloroacetate can attenuate skeletal muscle fatigue by up to 35% in a canine model of peripheral ischemia (Timmons, J.A., S.M. Poucher, D. Constantin-Teodosiu, V. Worrall,...
17.
Timmons J, Poucher S, Constantin-Teodosiu D, MacDonald I, Greenhaff P
Am J Physiol
. 1997 Aug;
273(2 Pt 1):E233-8.
PMID: 9277374
Skeletal muscle contraction during ischemia, such as that experienced by peripheral vascular disease patients, is characterized by rapid fatigue. Using a canine gracilis model, we tested the hypothesis that a...
18.
Constantin-Teodosiu D, Greenhaff P, McIntyre D, Round J, Jones D
Exp Physiol
. 1997 May;
82(3):593-601.
PMID: 9179576
Five subjects underwent twenty electrically evoked maximal isometric contractions of the anterior tibialis muscle of both legs (n = 10), with limb blood flow occluded. Measurements of muscle high-energy phosphates...
19.
Stroud M, Ritz P, Coward W, Sawyer M, Constantin-Teodosiu D, Greenhaff P, et al.
Eur J Appl Physiol Occup Physiol
. 1997 Jan;
76(3):243-52.
PMID: 9286604
Two men, R.F. and M.S., pulled sledges each with starting masses of 222 kg, 2300 km across Antarctica. Exercise was performed for approximately 10 h each day for 95 days....
20.
Casey A, Constantin-Teodosiu D, Howell S, Hultman E, Greenhaff P
Am J Physiol
. 1996 Jul;
271(1 Pt 1):E38-43.
PMID: 8760079
Nine male subjects performed two bouts of 30-s maximal isokinetic cycling. Each bout of exercise was performed at 80 revolutions/min and was separated by 4 min of recovery. Mixed-muscle phosphocreatine...