D A Carson
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Explore the profile of D A Carson including associated specialties, affiliations and a list of published articles.
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363
Citations
6777
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Recent Articles
1.
Saven A, Carrera C, Carson D, Beutler E, Piro L
Leuk Lymphoma
. 2016 Jul;
5 Suppl 1:133-8.
PMID: 27463495
Ninety patients with advanced refractory chronic lymphocytic leukemia (CLL) were treated with 2-chlorodeoxyadenosine (2-CdA) administered either as a 0.1 mg/kg/day 7-day continuous intravenous infusion or as a 0.028 mg to...
2.
Kipps T, Rassenti L, Duffy S, Kobayashi R, Martin T, Chen P, et al.
Leuk Lymphoma
. 2016 Jul;
5 Suppl 1:39-45.
PMID: 27463478
The malignant cells from most patients with B cell chronic lymphocytic leukemia (B-CLL) and related small lymphocytic lymphomas (SLL) co-express B cell differentiation antigens and the pan-T lymphocytes surface antigen...
3.
Beutler E, Piro L, Saven A, Kay A, McMillan R, Longmire R, et al.
Leuk Lymphoma
. 2016 Jul;
5(1):1-8.
PMID: 27463204
Hereditary adenosine deaminase deficiency results in failure of the lymphocyte development. This occurs because of the accumulation of deoxyadenine nucleotides in cells with high deoxycytidine kinase and low 5'-nucleotidase activity....
4.
Smith E, Ghia E, DeBoever C, Rassenti L, Jepsen K, Yoon K, et al.
Blood Cancer J
. 2015 Apr;
5:e303.
PMID: 25860294
We examined genetic and epigenetic changes that occur during disease progression from indolent to aggressive forms of chronic lymphocytic leukemia (CLL) using serial samples from 27 patients. Analysis of DNA...
5.
Tsoukas C, Valentine M, Lotz M, Vaughan J, Carson D
Immunol Today
. 2014 Oct;
5(11):311-3.
PMID: 25290752
Monoclonal antibodies raised against human T lymphocytes have identified several cell surface structures that are intimately involved in T-cell function. Perhaps the most familiar is the structure labelled T3. First...
6.
Carson D, Lakow E, Wasson D, Kamatani N
Immunol Today
. 2014 Oct;
2(12):234-8.
PMID: 25290650
Two inborn errors of purine metabolism have been associated with autosomally inherited human immunodeficiency diseases. A lack of adenosine deaminase (ADA) produces severe lymphopenia and a combined immunodeficiency syndrome. A...
7.
Sen M, Carson D
Mod Rheumatol
. 2014 Jan;
12(1):5-9.
PMID: 24383825
Abstract Rheumatoid arthritis (RA) is a joint-specific disease with complex pathogenesis. It is characterized by synovial inflammation, cartilage loss, and joint destruction. The reasons why joint damage recurs when therapy...
8.
Castro J, Prada C, Aguillon R, Kitada S, Fukuda T, Motta M, et al.
Leukemia
. 2006 Feb;
20(4):680-8.
PMID: 16498393
We compared antisense phosphorothioate oligonucleotides (PS-ODN) that target BCL-2 such as Genasense (G3139-PS), with other PS-ODN or phosphodiester-ODN (PO-ODN) in their relative capacity to induce apoptosis of chronic lymphocytic leukemia...
9.
Prakken B, Carson D, Albani S
Curr Dir Autoimmun
. 2002 Jan;
3:51-63.
PMID: 11791471
No abstract available.
10.
Van Uden J, Tran C, Carson D, Raz E
Eur J Immunol
. 2001 Dec;
31(11):3281-90.
PMID: 11745345
Immunostimulatory DNA sequences (ISS, CpG motifs) potently stimulate Th1 and cytotoxic T lymphocyte (CTL) responses to antigens and have thus generated considerable interest due to their potential use in immunotherapeutics....