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Cristina dAbramo

Explore the profile of Cristina dAbramo including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 592
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Recent Articles
1.
Freudenberg-Hua Y, Giliberto L, dAbramo C, Li W, Ma Y, Goate A, et al.
medRxiv . 2025 Mar; PMID: 40061357
Plasma levels of protein biomarkers glial fibrillary acidic protein (GFAP) and neurofilament light (NEFL) are key dementia biomarkers, but it is unclear how risk genes for Alzheimer's disease (AD) influence...
2.
Katel S, Cicalo J, Vasciaveo V, Carrion J, Leann M, Huerta P, et al.
bioRxiv . 2025 Mar; PMID: 40027607
Tau is a primary target for immunotherapy in Alzheimer's disease. Recent studies have shown the potential of anti-tau fragment antibodies in lowering pathological tau levels and . Here, we compared...
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Yesiltepe M, Yin T, Tambini M, Bao H, Pan M, dAbramo C, et al.
Cell Commun Signal . 2024 Sep; 22(1):458. PMID: 39334477
APOE is a major genetic factor in late-onset Alzheimer's disease (LOAD), with APOE4 increasing risk, APOE3 acting as neutral, and APOE2 offering protection. APOE also plays key role in lipid...
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Choudhary R, Shoaib M, Hayashida K, Yin T, Miyara S, dAbramo C, et al.
Cells . 2023 Jun; 12(11). PMID: 37296668
Background: Cardiac arrest (CA) can lead to neuronal degeneration and death through various pathways, including oxidative, inflammatory, and metabolic stress. However, current neuroprotective drug therapies will typically target only one...
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Tambini M, Yin T, Yesiltepe M, Breuillaud L, Zehntner S, dAbramo C, et al.
J Biol Chem . 2023 May; 299(7):104868. PMID: 37257821
About 2% of Alzheimer's disease (AD) cases have early onset (FAD) and are caused by mutations in either Presenilins (PSEN1/2) or amyloid-β precursor protein (APP). PSEN1/2 catalyze production of Aβ...
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Ivaldo C, Passalacqua M, Furfaro A, dAbramo C, Ruiz S, Chatterjee P, et al.
Sci Rep . 2023 Jan; 13(1):597. PMID: 36631513
Classical cadherins, including vascular endothelial (VE)-cadherin, are targeted by matrix metalloproteinases (MMPs) and γ-secretase during adherens junction (AJ) disassembly, a mechanism that might have relevance for endothelial cell (EC) integrity...
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dAbramo C, DAdamio L, Giliberto L
J Pers Med . 2020 Sep; 10(3). PMID: 32911755
Alzheimer's disease (AD) is the most common type of dementia, affecting more than 5 million Americans, with steadily increasing mortality and incredible socio-economic burden. Not only have therapeutic efforts so...
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Vitale F, Ortolan J, Volpe B, Marambaud P, Giliberto L, dAbramo C
Acta Neuropathol Commun . 2020 Aug; 8(1):126. PMID: 32762731
With evidence supporting the prion-like spreading of extracellular tau as a mechanism for the initiation and progression of Alzheimer's disease (AD), immunotherapy has emerged as a potential disease-modifying strategy to...
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Sankowski R, Strohl J, Huerta T, Nasiri E, Mazzarello A, dAbramo C, et al.
Proc Natl Acad Sci U S A . 2019 Dec; 116(51):25982-25990. PMID: 31792184
Retrotransposons compose a staggering 40% of the mammalian genome. Among them, endogenous retroviruses (ERV) represent sequences that closely resemble the proviruses created from exogenous retroviral infection. ERVs make up 8...