Craig M Forester
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Explore the profile of Craig M Forester including associated specialties, affiliations and a list of published articles.
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15
Citations
575
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Recent Articles
1.
Forester C, Oses-Prieto J, Phillips N, Miglani S, Pang X, Byeon G, et al.
Sci Adv
. 2022 Dec;
8(51):eadd3942.
PMID: 36563140
Translation control is essential in balancing hematopoietic precursors and differentiation; however, the mechanisms underlying this program are poorly understood. We found that the activity of the major cap-binding protein eIF4E...
2.
Tiu G, Kerr C, Forester C, Krishnarao P, Rosenblatt H, Raj N, et al.
Dev Cell
. 2021 Jul;
56(14):2089-2102.e11.
PMID: 34242585
In ribosomopathies, perturbed expression of ribosome components leads to tissue-specific phenotypes. What accounts for such tissue-selective manifestations as a result of mutations in the ribosome, a ubiquitous cellular machine, has...
3.
Forester C, Ruggero D
Cell Stem Cell
. 2021 Jul;
28(7):1183-1185.
PMID: 34214436
Protein synthesis regulation constitutes a key node in directing decisions between hematopoietic stemness and differentiation. In this issue of Cell Stem Cell, Lv et al. (2021) describe a mechanism by...
4.
McMahon M, Contreras A, Holm M, Uechi T, Forester C, Pang X, et al.
Elife
. 2019 Sep;
8.
PMID: 31478838
Small nucleolar RNAs (snoRNAs) are a diverse group of non-coding RNAs that direct chemical modifications at specific residues on other RNA molecules, primarily on ribosomal RNA (rRNA). SnoRNAs are altered...
5.
Balkin D, Poranki M, Forester C, Dorsey M, Slavotinek A, Pomerantz J
Mol Genet Genomic Med
. 2019 Jul;
7(9):e818.
PMID: 31350873
Background: Threonine Aspartase 1 (Taspase 1) is a highly conserved site-specific protease whose substrates are broad-acting nuclear transcription factors that govern diverse biological programs, such as organogenesis, oncogenesis, and tumor...
6.
Xu Y, Poggio M, Jin H, Shi Z, Forester C, Wang Y, et al.
Nat Med
. 2019 Jan;
25(2):301-311.
PMID: 30643286
Cancer cells develop mechanisms to escape immunosurveillance, among which modulating the expression of immune suppressive messenger RNAs is most well-documented. However, how this is molecularly achieved remains largely unresolved. Here,...
7.
Lal A, Wong T, Andrews J, Balasa V, Chung J, Forester C, et al.
Transfusion
. 2018 Sep;
58(12):2826-2835.
PMID: 30260477
Background: The severe forms of thalassemia are the most common inherited anemias managed with regular blood transfusion therapy. Transfusion policies and complications are critical to quality of life and survival,...
8.
Nguyen H, Conn C, Kye Y, Xue L, Forester C, Cowan J, et al.
Sci Transl Med
. 2018 May;
10(439).
PMID: 29720449
Oncogenic lesions up-regulate bioenergetically demanding cellular processes, such as protein synthesis, to drive cancer cell growth and continued proliferation. However, the hijacking of these key processes by oncogenic pathways imposes...
9.
Forester C, Zhao Q, Phillips N, Urisman A, Chalkley R, Oses-Prieto J, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(10):2353-2358.
PMID: 29467287
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that...
10.
Huang X, He Y, Dubuc A, Hashizume R, Zhang W, Reimand J, et al.
Nat Neurosci
. 2015 Aug;
18(9):1236-46.
PMID: 26258683
Over 20% of the drugs for treating human diseases target ion channels, but no cancer drug approved by the US Food and Drug Administration (FDA) is intended to target an...