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Craig Harris

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Articles 61
Citations 811
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Recent Articles
1.
Jackson D, Ulldemolins M, Liu X, Harris C, Tognolini A, Wallis S, et al.
Antimicrob Agents Chemother . 2024 Oct; 68(12):e0111624. PMID: 39480073
Patients undergoing elective pelvic exenteration surgery who receive piperacillin/tazobactam as surgical prophylaxis are at risk of suboptimal intraoperative antibiotic exposure. With this work, we aimed to study the plasma pharmacokinetics...
2.
Watt A, Kaushik V, Harris C, Yeung C, Lam Y, Osland E
Clin Nutr ESPEN . 2024 Jun; 62:88-94. PMID: 38901953
Background & Aims: Pelvic exenteration (PE) surgery is now a widely accepted procedure that is increasingly being performed worldwide but has significant morbidity. Although nutrition status, body mass index (BMI)...
3.
Crosignani S, Campos S, Bouix-Peter C, Harris C, Talbot E, Hu H, et al.
Bioorg Med Chem Lett . 2024 Feb; 100:129630. PMID: 38307441
A series of macrocyclic PKCθ inhibitors based on a 1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one hinge binder has been studied. Different aromatic and heteroaromatic substituents have been explored in order to optimize potency, isoform selectivity...
4.
Lapehn S, Colacino J, Harris C
Neurotoxicol Teratol . 2023 Jul; 99:107286. PMID: 37442398
Valproic acid (VPA) is an anti-epileptic medication that increases the risk of neural tube defect (NTD) outcomes in infants exposed during gestation. Previous studies into VPA's mechanism of action have...
5.
Clark D, Stevenson A, Lumley J, Petersen D, Harris C, Steffens D, et al.
ANZ J Surg . 2022 Feb; 92(1-2):19-20. PMID: 35212109
No abstract available.
6.
Clark D, Edmundson A, Steffens D, Harris C, Stevenson A, Solomon M
ANZ J Surg . 2022 Jan; 92(4):813-818. PMID: 34994080
Background: Anastomotic leak (AL) is the anathema of colorectal surgery. Early diagnosis is an essential segue to early intervention. A temporary diverting ileostomy (TDI) does not prevent an AL and...
7.
Piorczynski T, Lapehn S, Ringer K, Allen S, Johnson G, Call K, et al.
Neurotoxicol Teratol . 2021 Nov; 89:107039. PMID: 34737154
Valproic acid (VPA) is a widely prescribed medication that has traditionally been used to treat epilepsy, yet embryonic exposure to VPA increases the risk of the fetus developing neural tube...
8.
Lapehn S, Piorczynski T, Hansen J, Harris C
Reprod Toxicol . 2021 Mar; 101:81-92. PMID: 33713778
Redox regulation during metazoan development ensures that coordinated metabolic reprogramming and developmental signaling are orchestrated with high fidelity in the hypoxic embryonic environment. Valproic acid (VPA), an anti-seizure medication, is...
9.
Clark D, Yeoh E, Edmundson A, Harris C, Stevenson A, Steffens D, et al.
Ann Coloproctol . 2021 Jan; 38(2):124-132. PMID: 33445840
Purpose: Anastomotic leakage (AL) is the anathema of colorectal surgery. Its occurrence leads to increased morbidity and mortality and a prolonged hospital stay. Much work has gone into studying various...
10.
Neier K, Montrose L, Chen K, Malloy M, Jones T, Svoboda L, et al.
Environ Epigenet . 2021 Jan; 6(1):dvaa017. PMID: 33391822
Phthalates have been demonstrated to interfere with metabolism, presumably by interacting with peroxisome proliferator-activated receptors (PPARs). However, mechanisms linking developmental phthalate exposures to long-term metabolic effects have not yet been...