Costas Demetzos
Overview
Explore the profile of Costas Demetzos including associated specialties, affiliations and a list of published articles.
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Articles
144
Citations
891
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Recent Articles
11.
Hatziantoniou S, Demetzos C
Methods Mol Biol
. 2023 Feb;
2622:221-226.
PMID: 36781764
Liposomes are composed of different kinds of lipids or lipophilic substances and are used as carriers of bioactive molecules. The characterization of the prepared liposomes consists of the calculation of...
12.
Stampolaki M, Malwal S, Alvarez-Cabrera N, Gao Z, Moniruzzaman M, Babii S, et al.
ACS Infect Dis
. 2023 Jan;
9(2):342-364.
PMID: 36706233
SQ109 is a tuberculosis drug candidate that has high potency against and is thought to function at least in part by blocking cell wall biosynthesis by inhibiting the MmpL3 transporter....
13.
Chountoulesi M, Perinelli D, Forys A, Chrysostomou V, Kaminari A, Bonacucina G, et al.
Int J Pharm
. 2022 Nov;
630:122440.
PMID: 36436746
The abilities of sub-cellular targeting and stimuli-responsiveness are critical challenges in pharmaceutical nanotechnology. In the present study, glyceryl monooleate (GMO)-based non-lamellar lyotropic liquid crystalline nanoparticles were stabilized by the poly(2-(dimethylamino)ethyl...
14.
Chrysostomou V, Forys A, Trzebicka B, Demetzos C, Pispas S
Polymers (Basel)
. 2022 Nov;
14(22).
PMID: 36433029
Lipid-polymer chimeric (hybrid) nanosystems are promising platforms for the design of effective gene delivery vectors. In this regard, we developed DNA nanocarriers comprised of a novel poly[(stearyl methacrylate-co-oligo(ethylene glycol) methyl...
15.
Tziveleka L, Pippa N, Ioannou E, Demetzos C, Roussis V
J Funct Biomater
. 2022 Oct;
13(4).
PMID: 36278655
Liposomes, due to their safety profile and targeting ability, are among the most studied nanocarriers as antimicrobial delivery systems. However, due to lack of stability and the non-specific interaction of...
16.
Tsakiri M, Zivko C, Demetzos C, Mahairaki V
Front Pharmacol
. 2022 Aug;
13:900610.
PMID: 36016560
RNA-delivery is a promising tool to develop therapies for difficult to treat diseases such as neurological disorders, by silencing pathological genes or expressing therapeutic proteins. However, in many cases RNA...
17.
Maswadeh H, Khan A, Alorainy M, Al-Wabel N, Demetzos C
Drug Dev Ind Pharm
. 2022 Jul;
48(4):158-168.
PMID: 35834369
Thermosensitive liposomes loaded with cisplatin and doxorubicin composed of DPPC, DSPC, and DPPE-PEG5000 with different ratios were prepared by thin film hydration method. The Differential Scanning Calorimetry (DSC) curves showed...
18.
Pippa N, Lagopati N, Forys A, Chountoulesi M, Katifelis H, Chrysostomou V, et al.
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740250
Liposomes with adjuvant properties are utilized to carry biomolecules, such as proteins, that are often sensitive to the stressful conditions of liposomal preparation processes. The aim of the present study...
19.
Triantafyllopoulou E, Pippa N, Demetzos C
J Liposome Res
. 2022 Jun;
33(1):77-88.
PMID: 35730463
At the dawn of a new nanotechnological era in the pharmaceutical field, it is very important to examine and understand all the aspects that influence in vivo behaviour of nanoparticles....
20.
Palli V, Leonis G, Zoupanou N, Georgiou N, Chountoulesi M, Naziris N, et al.
Molecules
. 2022 Apr;
27(8).
PMID: 35458617
Losartan potassium salt (LSR) is a well-known antihypertensive drug with proven beneficial effects on human health. Its formulation with the non-toxic 2-hydroxypropyl-β-cyclodextrin (2-HP-β-CD) could improve its pharmacological profile. Thus, its...