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Aristidis Georgopoulos

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Articles 10
Citations 89
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Recent Articles
1.
Pandelidou M, Dimas K, Georgopoulos A, Hatziantoniou S, Demetzos C
J Nanosci Nanotechnol . 2011 Apr; 11(2):1259-66. PMID: 21456169
Curcumin has been associated with the treatment of various diseases in traditional medicine, among them cancer. The major problems that prevent its approval as therapeutic agent are its low water...
2.
Mourelatou E, Spyratou E, Georgopoulos A, Makropoulou M, Liandris E, Gazouli M, et al.
J Nanosci Nanotechnol . 2010 Dec; 10(9):5548-56. PMID: 21133073
Liposomes applications in health care include meanly their ability to carry drugs and genes inside the human body for therapeutic purposes. Nevertheless their applicability can extend far beyond and could...
3.
Patel N, Hatziantoniou S, Georgopoulos A, Demetzos C, Torchilin V, Weissig V, et al.
J Liposome Res . 2009 Nov; 20(3):244-9. PMID: 19883213
Current efforts toward improving the effectiveness of drug therapy are increasingly relying on drug-targeting strategies to effectively deliver bioactive molecules to their molecular targets. Pharmaceutical nanocarriers represent a major tool...
4.
Villalonga-Barber C, Micha-Screttas M, Steele B, Georgopoulos A, Demetzos C
Curr Top Med Chem . 2008 Oct; 8(14):1294-309. PMID: 18855710
Two general aspects which need to be considered for the successful application of dendrimers for biomedical purposes are their availability at an acceptable cost and their suitability as regards their...
5.
Markatou E, Gionis V, Chryssikos G, Hatziantoniou S, Georgopoulos A, Demetzos C
Int J Pharm . 2007 Apr; 339(1-2):231-6. PMID: 17428628
Dimethoxycurcumin, a lipophilic analog of curcumin found as a major pigment in the Indian species turmeric (Curcuma longa Linn.), is known to possess significant activity against various cancer cell lines,...
6.
Paradissis A, Hatziantoniou S, Georgopoulos A, Psarra A, Dimas K, Demetzos C
Biomed Pharmacother . 2007 Feb; 61(2-3):120-4. PMID: 17270382
The uptake of free and liposome-incorporated sclareol and its effect on the growth of human cancer cell line HCT-116 was investigated. Recovery of free and liposomal sclareol in cytosol, nuclei...
7.
Dimas K, Hatziantoniou S, Tseleni S, Khan H, Georgopoulos A, Alevizopoulos K, et al.
Apoptosis . 2007 Jan; 12(4):685-94. PMID: 17260186
Labd-14-ene-8, 13-diol (sclareol) is a labdane-type diterpene, which has demonstrated significant cytotoxic activity against human leukemic cell lines, but its effect on solid tumor-derived cells is uknown. Here, we demonstrate...
8.
Alexopoulou E, Georgopoulos A, Kagkadis K, Demetzos C
J Liposome Res . 2006 Mar; 16(1):17-25. PMID: 16556547
Liposomes composed of egg-phosphatidylcholine (EPC) incorporating quercetin (QR) were prepared by the thin-film hydration method (TFHM) and the monophase solution method (MSM). A rapid and slow freeze-drying process was applied...
9.
Hatziantoniou S, Dimas K, Georgopoulos A, Sotiriadou N, Demetzos C
Pharmacol Res . 2005 Oct; 53(1):80-7. PMID: 16253514
The aim of this study was to design and prepare liposome-incorporated sclareol--a highly lipophilic natural product-to overcome its water insolubility and develop suitable formulations for in vivo administration. The bioactive...
10.
Matsingou C, Hatziantoniou S, Georgopoulos A, Dimas K, Terzis A, Demetzos C
Chem Phys Lipids . 2005 Sep; 138(1-2):1-11. PMID: 16182267
Labd-13(E)-ene-8alpha,15-diol (1) and its derivative labd-13(E)-ene-8alpha-ol-15-yl-acetate (2) are water insoluble biological active molecules and their structures were elucidated using NMR and X-ray techniques. Differential scanning calorimetry (DSC) was applied to...