Connie L Jiang
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Explore the profile of Connie L Jiang including associated specialties, affiliations and a list of published articles.
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11
Citations
207
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Recent Articles
1.
Gallo P, Elliott E, Ford G, Biswas C, Wheaton J, Kim J, et al.
J Leukoc Biol
. 2024 Oct;
PMID: 39390898
Objective: Macrophage activation syndrome (MAS) is characterized by multi-lineage cytopenias, hypercytokinemia, and tissue hemophagocytosis. Transcription factor Nrf2 is a master regulator of redox homeostasis. In this work we aim to...
2.
Jain N, Goyal Y, Dunagin M, Cote C, Mellis I, Emert B, et al.
Cell Syst
. 2024 Feb;
15(2):109-133.e10.
PMID: 38335955
Pluripotency can be induced in somatic cells by the expression of OCT4, KLF4, SOX2, and MYC. Usually only a rare subset of cells reprogram, and the molecular characteristics of this...
3.
Richman L, Goyal Y, Jiang C, Raj A
Cell Genom
. 2023 Feb;
3(2):100247.
PMID: 36819662
Clustering cells based on their high-dimensional profiles is an important data reduction process by which researchers infer distinct cellular states. The advent of cellular barcoding, however, provides an alternative means...
4.
Jain N, Goyal Y, Dunagin M, Cote C, Mellis I, Emert B, et al.
bioRxiv
. 2023 Feb;
PMID: 36798299
Pluripotency can be induced in somatic cells by the expression of the four "Yamanaka" factors OCT4, KLF4, SOX2, and MYC. However, even in homogeneous conditions, usually only a rare subset...
5.
Dardani I, Emert B, Goyal Y, Jiang C, Kaur A, Lee J, et al.
Nat Methods
. 2022 Oct;
19(11):1403-1410.
PMID: 36280724
RNA labeling in situ has enormous potential to visualize transcripts and quantify their levels in single cells, but it remains challenging to produce high levels of signal while also enabling...
6.
Jiang C, Goyal Y, Jain N, Wang Q, Truitt R, Cote A, et al.
Genome Biol
. 2022 Apr;
23(1):90.
PMID: 35382863
Background: Cardiac differentiation of human-induced pluripotent stem (hiPS) cells consistently produces a mixed population of cardiomyocytes and non-cardiac cell types, even when using well-characterized protocols. We sought to determine whether...
7.
Emert B, Cote C, Torre E, Dardani I, Jiang C, Jain N, et al.
Nat Biotechnol
. 2021 Feb;
39(7):865-876.
PMID: 33619394
Molecular differences between individual cells can lead to dramatic differences in cell fate, such as death versus survival of cancer cells upon drug treatment. These originating differences remain largely hidden...
8.
Torre E, Arai E, Bayatpour S, Jiang C, Beck L, Emert B, et al.
Nat Genet
. 2021 Jan;
53(1):76-85.
PMID: 33398196
Cellular plasticity describes the ability of cells to transition from one set of phenotypes to another. In melanoma, transient fluctuations in the molecular state of tumor cells mark the formation...
9.
Rouhanifard S, Mellis I, Dunagin M, Bayatpour S, Jiang C, Dardani I, et al.
Nat Biotechnol
. 2019 Jan;
37(1):102.
PMID: 30605160
No abstract available.
10.
Rouhanifard S, Mellis I, Dunagin M, Bayatpour S, Jiang C, Dardani I, et al.
Nat Biotechnol
. 2018 Nov;
PMID: 30418432
Methods for detecting single nucleic acids in cell and tissues, such as fluorescence in situ hybridization (FISH), are limited by relatively low signal intensity and nonspecific probe binding. Here we...