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Congling Chen

Explore the profile of Congling Chen including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 19
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Recent Articles
1.
Chen C, Zhang Y, Fan Y, Ying Z, Su Q, Li X, et al.
Front Endocrinol (Lausanne) . 2023 May; 14:1108442. PMID: 37214244
Background & Aims: The effect of change in non-alcoholic fatty liver disease (NAFLD) status on incident diabetes has not been well studied. We aimed to investigate the association of NAFLD...
2.
Sharma I, Chen C, Daraji D, Horn J, Hagen T
Bioorg Med Chem Lett . 2023 Apr; 87:129281. PMID: 37031729
Methionine aminopeptidases (MetAp) are dinuclear metalloenzymes found in both prokaryotes and eukaryotes that catalyze the hydrolysis of the N-terminal methionine residue from nascent proteins, an important post-translational modification, which makes...
3.
Fan Y, Zhang Y, Chen C, Ying Z, Su Q, Li X, et al.
Hepatol Res . 2023 Feb; 53(6):479-488. PMID: 36745152
Aim: The association between sugar-sweetened beverages and metabolic disorders has been well studied. However, it has not been determined whether fasting serum fructose is associated with metabolic dysfunction-associated fatty liver...
4.
Hu J, Tan S, Lim M, Chang S, Cui G, Liu S, et al.
Biochem J . 2018 May; 475(11):1965-1977. PMID: 29760237
AP-2 gamma (AP-2γ) is a transcription factor that plays pivotal roles in breast cancer biology. To search for small molecule inhibitors of AP-2γ, we performed a high-throughput fluorescence anisotropy screen...
5.
Helgren T, Seven E, Chen C, Edwards T, Staker B, Abendroth J, et al.
Bioorg Med Chem Lett . 2018 Mar; 28(8):1376-1380. PMID: 29551481
Methionine aminopeptidase (MetAP) is a dinuclear metalloprotease responsible for the cleavage of methionine initiator residues from nascent proteins. MetAP activity is necessary for bacterial proliferation and is therefore a projected...
6.
Helgren T, Chen C, Wangtrakuldee P, Edwards T, Staker B, Abendroth J, et al.
Bioorg Med Chem . 2017 Jan; 25(3):813-824. PMID: 28089350
Methionine aminopeptidase (MetAP) is a class of ubiquitous enzymes essential for the survival of numerous bacterial species. These enzymes are responsible for the cleavage of N-terminal formyl-methionine initiators from nascent...