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Colleen M Croniger

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Articles 44
Citations 1900
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Recent Articles
11.
DeSantis D, Ko C, Wang L, Lee P, Croniger C
Mediators Inflamm . 2015 Dec; 2015:909827. PMID: 26635450
TThe molecular mechanisms responsible for the development of hepatic fibrosis are not fully understood. The Nlrc4 inflammasome detects cytosolic presence of bacterial components, activating inflammatory cytokines to facilitate clearance of...
12.
Gao Y, Erokwu B, DeSantis D, Croniger C, Schur R, Lu L, et al.
NMR Biomed . 2015 Nov; 29(1):84-9. PMID: 26608869
Autosomal recessive polycystic kidney disease (ARPKD) is a potentially lethal multi-organ disease affecting both the kidneys and the liver. Unfortunately, there are currently no non-invasive methods to monitor liver disease...
13.
Omenetti S, Brogi M, Goodman W, Croniger C, Eid S, Huang A, et al.
Cell Mol Gastroenterol Hepatol . 2015 Jul; 1(4):406-419. PMID: 26213712
Background And Aims: Liver inflammation is a common extraintestinal manifestation of inflammatory bowel disease (IBD); however, whether liver involvement is a consequence of a primary intestinal defect or results from...
14.
De S, Zhou H, DeSantis D, Croniger C, Li X, Stark G
Proc Natl Acad Sci U S A . 2015 Jul; 112(31):9680-5. PMID: 26195767
Several components of the canonical pathway of response to lipopolysaccharide (LPS) are required for the EGF-dependent activation of NFκB. Conversely, the ability of Toll-like Receptor 4 (TLR4) to activate NFκB...
15.
Feng X, Scott A, Wang Y, Wang L, Zhao Y, Doerner S, et al.
PLoS One . 2014 Jun; 9(6):e100783. PMID: 24949727
Obesity is a risk factor for many human diseases. However, the underlying molecular causes of obesity are not well understood. Here, we report that protein tyrosine phosphatase receptor T (PTPRT)...
16.
DeSantis D, Ko C, Liu Y, Liu X, Hise A, Nunez G, et al.
Mediators Inflamm . 2014 Jan; 2013:751374. PMID: 24453428
Alcoholic liver disease (ALD) is characterized by increased hepatic lipid accumulation (steatosis) and inflammation with increased expression of proinflammatory cytokines. Two of these cytokines, interleukin-1 β (IL-1 β ) and...
17.
Marwarha G, Berry D, Croniger C, Noy N
FASEB J . 2013 Sep; 28(1):26-34. PMID: 24036882
Vitamin A, retinol, circulates in blood bound to retinol-binding protein (RBP). At some tissues, holo-RBP is recognized by a plasma membrane receptor termed STRA6, which serves a dual role: it...
18.
Berry D, Jacobs H, Marwarha G, Gely-Pernot A, OByrne S, DeSantis D, et al.
J Biol Chem . 2013 Jul; 288(34):24528-39. PMID: 23839944
The plasma membrane protein STRA6 is thought to mediate uptake of retinol from its blood carrier retinol-binding protein (RBP) into cells and to function as a surface receptor that, upon...
19.
DeSantis D, Lee P, Doerner S, Ko C, Kawasoe J, Hill-Baskin A, et al.
Alcohol Clin Exp Res . 2013 Jun; 37(10):1668-79. PMID: 23763294
Background: Because the histological and biochemical progression of liver disease is similar in alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH), we hypothesized that the genetic susceptibility to these liver diseases...
20.
Krokowski D, Han J, Saikia M, Majumder M, Yuan C, Guan B, et al.
J Biol Chem . 2013 May; 288(24):17202-13. PMID: 23645676
Endoplasmic reticulum (ER) stress-induced responses are associated with the loss of insulin-producing β-cells in type 2 diabetes mellitus. β-Cell survival during ER stress is believed to depend on decreased protein...