Colette Quinn
Overview
Explore the profile of Colette Quinn including associated specialties, affiliations and a list of published articles.
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11
Citations
92
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Recent Articles
1.
DAtri V, Imiolek M, Quinn C, Finny A, Lauber M, Fekete S, et al.
J Chromatogr A
. 2024 Apr;
1722:464862.
PMID: 38581978
The 21st century has been particularly productive for the biopharmaceutical industry, with the introduction of several classes of innovative therapeutics, such as monoclonal antibodies and related compounds, gene therapy products,...
2.
Joshipura I, Nguyen C, Quinn C, Yang J, Morales D, Santiso E, et al.
iScience
. 2023 Apr;
26(4):106493.
PMID: 37091232
Metals tend to supercool-that is, they freeze at temperatures below their melting points. In general, supercooling is less favorable when liquids are in contact with nucleation sites such as rough...
3.
Lin H, Parkinson D, Holman J, Thompson W, Anderson C, Hadfield M, et al.
PLoS One
. 2023 Mar;
18(3):e0271008.
PMID: 36930604
Differential scanning calorimetry (DSC) can indicate changes in structure and/or concentration of the most abundant proteins in a biological sample via heat denaturation curves (HDCs). In blood serum for example,...
4.
Fujii T, Reiling C, Quinn C, Kliman M, Mendelsohn B, Matsuda Y
Explor Target Antitumor Ther
. 2022 Sep;
2(6):576-585.
PMID: 36046112
Aim: Direct analytical comparison of two major drug-linkers in the antibody-drug conjugate (ADC) field was conducted. Methods: Four different analytical methods [AlogP calculation, reverse phase (RP) high-performance liquid chromatography (HPLC;...
5.
Liu H, Iketani S, Zask A, Khanizeman N, Bednarova E, Forouhar F, et al.
Nat Commun
. 2022 Apr;
13(1):1891.
PMID: 35393402
The SARS-CoV-2 3CL protease is a critical drug target for small molecule COVID-19 therapy, given its likely druggability and essentiality in the viral maturation and replication cycle. Based on the...
6.
Hansen L, Quinn C
Eur Biophys J
. 2019 Sep;
48(8):825-835.
PMID: 31555842
Acquisition of precise and accurate results by isothermal titration calorimetry (ITC) can be achieved through thoughtful experimental design and modeling and careful experimental operations. Large reported errors in ITC results...
7.
Prather L, Weerasekare G, Sima M, Quinn C, Stewart R
Polymers (Basel)
. 2019 Apr;
11(4).
PMID: 30970637
Protamines are natural polyguanidiniums, arginine(R)-rich proteins involved in the compaction of chromatin during vertebrate spermatogenesis. Salmine, a protamine isolated from salmon sperm, contains 65 mol% R residues, with positively charged...
8.
Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms
Siddiqui-Jain A, Hoj J, Hargiss J, Hoj T, Payne C, Ritchie C, et al.
Bioorg Med Chem Lett
. 2017 Aug;
27(17):3992-4000.
PMID: 28780159
Stimulation of cultured epithelial cells with scatter factor/hepatocyte growth factor (HGF) results in individual cells detaching and assuming a migratory and invasive phenotype. Epithelial scattering recapitulates cancer progression and studies...
9.
Hansen L, Transtrum M, Quinn C, Demarse N
Biochim Biophys Acta
. 2016 Jan;
1860(5):957-966.
PMID: 26721335
Background: Isothermal calorimetry allows monitoring of reaction rates via direct measurement of the rate of heat produced by the reaction. Calorimetry is one of very few techniques that can be...
10.
Transtrum M, Hansen L, Quinn C
Methods
. 2014 Dec;
76:194-200.
PMID: 25497059
The purposes of this paper are (a) to examine the effect of calorimeter time constant (τ) on heat rate data from a single enzyme injection into substrate in an isothermal...