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David H Parkinson

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Recent Articles
1.
Haliyur R, Parkinson D, Ma F, Xu J, Li Q, Huang Y, et al.
Ophthalmol Sci . 2024 Sep; 4(6):100539. PMID: 39220810
Purpose: Current therapies for proliferative diabetic retinopathy (PDR) do not specifically target VEGF-independent, cell-type-specific processes that lead to vision loss, such as inflammatory pathways. This study aimed to identify targetable...
2.
Roden R, Zuniga N, Wright J, Parkinson D, Jiang F, Patil L, et al.
Clin Proteomics . 2024 Mar; 21(1):23. PMID: 38481131
Background: Human tear protein biomarkers are useful for detecting ocular and systemic diseases. Unfortunately, existing tear film sampling methods (Schirmer strip; SS and microcapillary tube; MCT) have significant drawbacks, such...
3.
Giacalone J, Parkinson D, Balikov D, Rao R
Int Ophthalmol Clin . 2023 Dec; 64(1):21-33. PMID: 38146879
No abstract available.
4.
Patil L, Parkinson D, Zuniga N, Lin H, Naylor B, Price J
J Chromatogr A . 2023 May; 1701:464044. PMID: 37196519
Offline peptide separation (PS) using high-performance liquid chromatography (HPLC) is currently used to enhance liquid chromatography-tandem mass spectrometry (LC-MS/MS) detection of proteins. In search of more effective methods for enhancing...
5.
Lin H, Parkinson D, Holman J, Thompson W, Anderson C, Hadfield M, et al.
PLoS One . 2023 Mar; 18(3):e0271008. PMID: 36930604
Differential scanning calorimetry (DSC) can indicate changes in structure and/or concentration of the most abundant proteins in a biological sample via heat denaturation curves (HDCs). In blood serum for example,...
6.
Naylor B, Anderson C, Hadfield M, Parkinson D, Ahlstrom A, Hannemann A, et al.
J Proteome Res . 2022 Sep; 21(11):2703-2714. PMID: 36099490
The synthesis of new proteins and the degradation of old proteins in vivo can be quantified in serial samples using metabolic isotope labeling to measure turnover. Because serial biopsies in...