Clotilde Billottet
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Explore the profile of Clotilde Billottet including associated specialties, affiliations and a list of published articles.
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19
Citations
399
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Recent Articles
1.
Dantzer C, Dif L, Vache J, Basbous S, Billottet C, Moreau V
Br J Cancer
. 2024 Sep;
131(12):1871-1880.
PMID: 39261716
CTNNB1, encoding the ß-catenin protein, is a key oncogene contributing to liver carcinogenesis. Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer in adult, representing the third...
2.
Dantzer C, Vache J, Brunel A, Mahouche I, Raymond A, Dupuy J, et al.
Elife
. 2024 Jul;
13.
PMID: 39008536
Immune checkpoint inhibitors have produced encouraging results in cancer patients. However, the majority of ß-catenin-mutated tumors have been described as lacking immune infiltrates and resistant to immunotherapy. The mechanisms by...
3.
Lorusso G, Wyss C, Kuonen F, Vannini N, Billottet C, Duffey N, et al.
Sci Transl Med
. 2022 Sep;
14(661):eaax8933.
PMID: 36070364
Brain metastasis is a complication of increasing incidence in patients with breast cancer at advanced disease stage. It is a severe condition characterized by a rapid decline in quality of...
4.
Campion O, Thevenard Devy J, Billottet C, Schneider C, Etique N, Dupuy J, et al.
Biomedicines
. 2021 Oct;
9(10).
PMID: 34680548
Background: LRP-1 is a multifunctional scavenger receptor belonging to the LDLR family. Due to its capacity to control pericellular levels of various growth factors and proteases, LRP-1 plays a crucial...
5.
Bikfalvi A, Billottet C
Am J Physiol Cell Physiol
. 2020 Jan;
318(3):C542-C554.
PMID: 31913695
Chemokines are a family of soluble cytokines that act as chemoattractants to guide the migration of cells, in particular of immune cells. However, chemokines are also involved in cell proliferation,...
6.
Boye K, Pujol N, Alves I, Chen Y, Daubon T, Lee Y, et al.
Nat Commun
. 2017 Nov;
8(1):1571.
PMID: 29146996
CXCR3 plays important roles in angiogenesis, inflammation, and cancer. However, the precise mechanism of regulation and activity in tumors is not well known. We focused on CXCR3-A conformation and on...
7.
Chen Y, Wu H, Boye K, Pan C, Chen Y, Pujol N, et al.
ACS Chem Biol
. 2017 Sep;
12(11):2767-2778.
PMID: 28945356
CXCL4 chemokines have antiangiogenic properties, mediated by different mechanisms, including CXCR3 receptor activation. Chemokines have distinct oligomerization states that are correlated with their biological functions. CXCL4 exists as a stable...
8.
Quemener C, Baud J, Boye K, Dubrac A, Billottet C, Soulet F, et al.
Cancer Res
. 2016 Sep;
76(22):6507-6519.
PMID: 27634764
The CXCL4 paralog CXCL4L1 is a less studied chemokine that has been suggested to exert an antiangiogenic function. However, CXCL4L1 is also expressed in patient tumors, tumor cell lines, and...
9.
Spuul P, Chi P, Billottet C, Chou C, Genot E
Methods
. 2015 Sep;
94:65-74.
PMID: 26342258
The study of cell behavior in constricted environment is particularly relevant to our understanding of the mechanisms of cell invasion. In this regard, microfluidic systems offer promising platforms as microfabricated...
10.
Billottet C, Quemener C, Bikfalvi A
Biochim Biophys Acta
. 2013 Sep;
1836(2):287-95.
PMID: 23994549
CXC chemokines are involved in chemotaxis, regulation of cell growth, induction of apoptosis and modulation of angiostatic effects. CXCL9, CXCL10, CXCL11, CXCL4 and its variant CXCL4L1 are members of the...