Claudia Figueroa-Romero
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Explore the profile of Claudia Figueroa-Romero including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Capocchi J, Figueroa-Romero C, Dunham S, Faraci G, Rothman J, Whiteson K, et al.
J Neurosci
. 2024 Oct;
44(41).
PMID: 39384409
Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRDs) are broad-impact multifactorial neurodegenerative diseases. Their complexity presents unique challenges for developing effective therapies. This review highlights research presented at the 2024...
2.
Guo K, Figueroa-Romero C, Noureldein M, Murdock B, Savelieff M, Hur J, et al.
Brain
. 2023 Sep;
147(2):665-679.
PMID: 37721161
Amyotrophic lateral sclerosis (ALS) is a complex, fatal neurodegenerative disease. Disease pathophysiology is incompletely understood but evidence suggests gut dysbiosis occurs in ALS, linked to impaired gastrointestinal integrity, immune system...
3.
Guo K, Figueroa-Romero C, Noureldein M, Hinder L, Sakowski S, Rumora A, et al.
Microbiome
. 2023 Mar;
11(1):52.
PMID: 36922895
Background: Peripheral neuropathy (PN) is a common complication in obesity, prediabetes, and type 2 diabetes, though its pathogenesis remains incompletely understood. In a murine high-fat diet (HFD) obesity model of...
4.
Hur J, Paez-Colasante X, Figueroa-Romero C, Lo T, Barmada S, Paulsen M, et al.
Hum Mol Genet
. 2022 Oct;
32(6):934-947.
PMID: 36219176
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Its complex pathogenesis and phenotypic heterogeneity hinder therapeutic development and early diagnosis. Altered RNA metabolism is a recurrent pathophysiologic theme, including...
5.
Figueroa-Romero C, Monteagudo A, Murdock B, Famie J, Webber-Davis I, Piecuch C, et al.
Front Immunol
. 2022 Feb;
13:773288.
PMID: 35197969
Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative disease with few therapeutic options. However, the immune system, including natural killer (NK) cells, is linked to ALS progression and...
6.
Lo T, Figueroa-Romero C, Hur J, Pacut C, Stoll E, Spring C, et al.
Front Mol Neurosci
. 2021 Nov;
14:739016.
PMID: 34776863
Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and molecular observations suggest that ALS pathology originates at a single site and spreads in an organized and prion-like manner, possibly...
7.
Paez-Colasante X, Figueroa-Romero C, Rumora A, Hur J, Mendelson F, Hayes J, et al.
Front Cell Neurosci
. 2020 Jun;
14:117.
PMID: 32477070
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, and incurable neurodegenerative disease. Recent studies suggest that dysregulation of gene expression by microRNAs (miRNAs) may play an important role in ALS...
8.
Figueroa-Romero C, Mikhail K, Gennings C, Curtin P, Bello G, Botero T, et al.
Ann Clin Transl Neurol
. 2020 May;
7(6):872-882.
PMID: 32438517
Objective: Deficiencies and excess of essential elements and toxic metals are implicated in amyotrophic lateral sclerosis (ALS), but the age when metal dysregulation appears remains unknown. This study aims to...
9.
Curtin P, Austin C, Curtin A, Gennings C, Figueroa-Romero C, Mikhail K, et al.
PLoS Comput Biol
. 2020 Apr;
16(4):e1007773.
PMID: 32294079
Evolutionarily conserved mechanisms maintain homeostasis of essential elements, and are believed to be highly time-variant. However, current approaches measure elemental biomarkers at a few discrete time-points, ignoring complex higher-order dynamical...
10.
Figueroa-Romero C, Guo K, Murdock B, Paez-Colasante X, Bassis C, Mikhail K, et al.
Dis Model Mech
. 2019 Oct;
13(2).
PMID: 31597644
Amyotrophic lateral sclerosis (ALS) is a terminal neurodegenerative disease. Genetic predisposition, epigenetic changes, aging and accumulated life-long environmental exposures are known ALS risk factors. The complex and dynamic interplay between...