Lucy M Hinder
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Explore the profile of Lucy M Hinder including associated specialties, affiliations and a list of published articles.
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30
Citations
1073
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Recent Articles
1.
Eid S, Elzinga S, Guo K, Hinder L, Hayes J, Pacut C, et al.
Transl Res
. 2024 Mar;
270():24-41.
PMID: 38556110
Peripheral neuropathy (PN) is a severe and frequent complication of obesity, prediabetes, and type 2 diabetes characterized by progressive distal-to-proximal peripheral nerve degeneration. However, a comprehensive understanding of the mechanisms...
2.
Elzinga S, Eid S, McGregor B, Jang D, Hinder L, Dauch J, et al.
Dis Model Mech
. 2023 Oct;
16(10).
PMID: 37791586
Diabetic kidney disease (DKD) and diabetic peripheral neuropathy (DPN) are common complications of type 1 (T1D) and type 2 (T2D) diabetes. However, the mechanisms underlying pathogenesis of these complications are...
3.
Eid S, Noureldein M, Kim B, Hinder L, Mendelson F, Hayes J, et al.
J Neurochem
. 2023 Jun;
166(2):367-388.
PMID: 37328915
Schwann cells (SCs) support peripheral nerves under homeostatic conditions, independent of myelination, and contribute to damage in prediabetic peripheral neuropathy (PN). Here, we used single-cell RNA sequencing to characterize the...
4.
Guo K, Figueroa-Romero C, Noureldein M, Hinder L, Sakowski S, Rumora A, et al.
Microbiome
. 2023 Mar;
11(1):52.
PMID: 36922895
Background: Peripheral neuropathy (PN) is a common complication in obesity, prediabetes, and type 2 diabetes, though its pathogenesis remains incompletely understood. In a murine high-fat diet (HFD) obesity model of...
5.
Rumora A, Guo K, Hinder L, OBrien P, Hayes J, Hur J, et al.
Front Physiol
. 2022 Sep;
13:921942.
PMID: 36072849
As the prevalence of prediabetes and type 2 diabetes (T2D) continues to increase worldwide, accompanying complications are also on the rise. The most prevalent complication, peripheral neuropathy (PN), is a...
6.
Eid S, OBrien P, Hinder L, Hayes J, Mendelson F, Zhang H, et al.
J Transl Sci
. 2021 Apr;
7(1).
PMID: 33868719
Diabetes is a global healthcare problem associated with enormous healthcare and personal costs. Despite glucose lowering agents that control glycaemia, both type 1 (T1D) and type (T2D) diabetes patients often...
7.
Eid S, Hinder L, Zhang H, Eksi R, Nair V, Eddy S, et al.
FASEB J
. 2021 Mar;
35(5):e21467.
PMID: 33788970
Diabetic kidney disease (DKD) and diabetic peripheral neuropathy (DPN) are two common diabetic complications. However, their pathogenesis remains elusive and current therapies are only modestly effective. We evaluated genome-wide expression...
8.
Sajic M, Rumora A, Kanhai A, Dentoni G, Varatharajah S, Casey C, et al.
J Neurosci
. 2021 Mar;
41(19):4321-4334.
PMID: 33785643
Peripheral neuropathy (PN) is the most common complication of prediabetes and diabetes. PN causes severe morbidity for Type 2 diabetes (T2D) and prediabetes patients, including limb pain followed by numbness...
9.
Eid S, OBrien P, Hinder L, Hayes J, Mendelson F, Zhang H, et al.
Biology (Basel)
. 2020 Oct;
9(11).
PMID: 33105667
Microvascular complications account for the significant morbidity associated with diabetes. Despite tight glycemic control, disease risk remains especially in type 2 diabetes (T2D) patients and no therapy fully prevents nerve,...
10.
OBrien P, Guo K, Eid S, Rumora A, Hinder L, Hayes J, et al.
Dis Model Mech
. 2019 Dec;
13(2).
PMID: 31822493
Peripheral neuropathy (PN) is a complication of prediabetes and type 2 diabetes (T2D). Increasing evidence suggests that factors besides hyperglycaemia contribute to PN development, including dyslipidaemia. The objective of this...