Claudia Agarinis
Overview
Explore the profile of Claudia Agarinis including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
405
Followers
0
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Recent Articles
1.
Neuwirt E, Magnani G, Cikovic T, Wohrle S, Fischer L, Kostina A, et al.
Sci Signal
. 2023 Jan;
16(768):eabh1083.
PMID: 36649377
Inflammasomes are intracellular protein complexes that promote an inflammatory host defense in response to pathogens and damaged or neoplastic tissues and are implicated in inflammatory disorders and therapeutic-induced toxicity. We...
2.
Zeng F, Beck V, Schuierer S, Garnier I, Manneville C, Agarinis C, et al.
Cells
. 2020 Dec;
9(12).
PMID: 33291479
Genetic knock-in using homology-directed repair is an inefficient process, requiring the selection of few modified cells and hindering its application to primary cells. Here, we describe Homology independent gene Tagging...
3.
Moutsatsos I, Hossain I, Agarinis C, Harbinski F, Abraham Y, Dobler L, et al.
SLAS Discov
. 2016 Dec;
22(3):238-249.
PMID: 27899692
High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such...
4.
Stein C, Bardet A, Roma G, Bergling S, Clay I, Ruchti A, et al.
PLoS Genet
. 2015 Aug;
11(8):e1005465.
PMID: 26295846
YAP1 is a major effector of the Hippo pathway and a well-established oncogene. Elevated YAP1 activity due to mutations in Hippo pathway components or YAP1 amplification is observed in several...
5.
Marti P, Stein C, Blumer T, Abraham Y, Dill M, Pikiolek M, et al.
Hepatology
. 2015 Jul;
62(5):1497-510.
PMID: 26173433
Unlabelled: The Yes-associated protein (YAP)/Hippo pathway has been implicated in tissue development, regeneration, and tumorigenesis. However, its role in cholangiocarcinoma (CC) is not established. We show that YAP activation is...
6.
Didiot M, Agarinis C, Varin T, Wu H, Nelson T, Selinger D, et al.
Assay Drug Dev Technol
. 2013 Aug;
11(6):355-66.
PMID: 23906347
The use of small molecules to modulate cellular processes is a powerful approach to investigate gene function as a complement to genetic approaches. The discovery and characterization of compounds that...
7.
Sury M, Vorlet-Fawer L, Agarinis C, Yousefi S, Grandgirard D, Leib S, et al.
Neurobiol Dis
. 2010 Sep;
41(1):201-8.
PMID: 20875857
Pneumococcal meningitis causes apoptosis of developing neurons in the dentate gyrus of the hippocampus. The death of these cells is accompanied with long-term learning and memory deficits in meningitis survivors....
8.
Sury M, Agarinis C, Widmer H, Leib S, Christen S
Neurobiol Dis
. 2008 Aug;
32(1):142-50.
PMID: 18703144
Pneumococcal meningitis is associated with caspase 3-dependent apoptosis of recently post-mitotic immature neurons in the dentate gyrus of the hippocampus. The death of these cells is implicated in the learning...