Clara Sa-Miranda
Overview
Explore the profile of Clara Sa-Miranda including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
710
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0
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Recent Articles
1.
Pereira C, Sa-Miranda C, De Libero G, Mori L, Macedo M
Eur J Immunol
. 2015 Oct;
46(1):147-53.
PMID: 26426881
Globotriaosylceramide (Gb3) is a glycosphingolipid present in cellular membranes that progressively accumulates in Fabry disease. Invariant Natural Killer T (iNKT) cells are a population of lipid-specific T cells that are...
2.
Mar F, da Silva T, Morgado M, Rodrigues L, Rodrigues D, Pereira M, et al.
Mol Neurobiol
. 2015 Jan;
53(2):1052-1064.
PMID: 25579385
Lack of axon regeneration following spinal cord injury has been mainly ascribed to the inhibitory environment of the injury site, i.e., to chondroitin sulfate proteoglycans (CSPGs) and myelin-associated inhibitors (MAIs)....
3.
Francisco T, Rodrigues T, Freitas M, Grou C, Carvalho A, Sa-Miranda C, et al.
J Biol Chem
. 2013 Aug;
288(40):29151-9.
PMID: 23963456
Peroxisomal matrix proteins are synthesized on cytosolic ribosomes and post-translationally targeted to the organelle by PEX5, the peroxisomal shuttling receptor. The pathway followed by PEX5 during this process is known...
4.
Pereira C, Azevedo O, Maia M, Dias A, Sa-Miranda C, Macedo M
Mol Genet Metab
. 2013 Feb;
108(4):241-8.
PMID: 23433711
Fabry disease is a lysosomal storage disease belonging to the group of sphingolipidoses. In Fabry disease there is accumulation of mainly globotriaosylceramide due to deficiency of the lysosomal enzyme α-galactosidase...
5.
Pinto M, Carvalho A, Grou C, Rodriguez-Borges J, Sa-Miranda C, Azevedo J
Biochim Biophys Acta
. 2012 Aug;
1823(10):1958-66.
PMID: 22867988
Covalent conjugation of the small ubiquitin-like modifier (SUMO) to proteins is a highly dynamic and reversible process. Cells maintain a fine-tuned balance between SUMO conjugation and deconjugation. In response to...
6.
Grou C, Francisco T, Rodrigues T, Freitas M, Pinto M, Carvalho A, et al.
J Biol Chem
. 2012 Feb;
287(16):12815-27.
PMID: 22371489
Peroxin 5 (PEX5), the peroxisomal protein shuttling receptor, binds newly synthesized peroxisomal matrix proteins in the cytosol and promotes their translocation across the organelle membrane. During the translocation step, PEX5...
7.
Carvalho A, Pinto M, Grou C, Vitorino R, Domingues P, Yamao F, et al.
Mol Biotechnol
. 2011 Oct;
51(3):254-61.
PMID: 22012022
Research in the ubiquitin field requires large amounts of ubiquitin-activating enzyme (E1) for in vitro ubiquitination assays. Typically, the mammalian enzyme is either isolated from natural sources or produced recombinantly...
8.
Freitas M, Francisco T, Rodrigues T, Alencastre I, Pinto M, Grou C, et al.
J Biol Chem
. 2011 Oct;
286(47):40509-19.
PMID: 21976670
Newly synthesized peroxisomal matrix proteins are targeted to the organelle by PEX5. PEX5 has a dual role in this process. First, it acts as a soluble receptor recognizing these proteins...
9.
Pinto M, Grou C, Fransen M, Sa-Miranda C, Azevedo J
Biochim Biophys Acta
. 2009 Sep;
1793(11):1669-75.
PMID: 19715730
According to current models, most newly synthesized peroxisomal intrinsic membrane proteins are recognized in the cytosol and targeted to the peroxisomal membrane by PEX19. At the organelle membrane the PEX19-cargo...
10.
Alencastre I, Rodrigues T, Grou C, Fransen M, Sa-Miranda C, Azevedo J
J Biol Chem
. 2009 Jul;
284(40):27243-51.
PMID: 19632994
Newly synthesized peroxisomal matrix proteins are targeted to the organelle by PEX5, the peroxisomal cycling receptor. Over the last few years, valuable data on the mechanism of this process have...