Clair D Geary
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Explore the profile of Clair D Geary including associated specialties, affiliations and a list of published articles.
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15
Citations
724
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Recent Articles
1.
Docampo M, da Silva M, Lazrak A, Nichols K, Lieberman S, Slingerland A, et al.
Blood
. 2021 Oct;
139(15):2392-2405.
PMID: 34653248
The intestinal microbiota is essential for the fermentation of dietary fiber into short-chain fatty acids (SCFA) such as butyrate, acetate, and propionate. SCFAs can bind to the G-protein-coupled receptors GPR43...
2.
Wiedemann G, Geary C, Lau C, Sun J
J Immunol
. 2020 May;
205(1):21-25.
PMID: 32461239
NK cells represent a cellular component of innate immunity but possess features of adaptive immunity, including clonal expansion and establishment of long-lived memory following infection. During mouse CMV (MCMV) infection,...
3.
Adams N, Geary C, Santosa E, Lumaquin D, Le Luduec J, Sottile R, et al.
Immunity
. 2019 May;
50(6):1381-1390.e5.
PMID: 31103381
The process of affinity maturation, whereby T and B cells bearing antigen receptors with optimal affinity to the relevant antigen undergo preferential expansion, is a key feature of adaptive immunity....
4.
Geary C, Krishna C, Lau C, Adams N, Gearty S, Pritykin Y, et al.
Cell Rep
. 2018 Aug;
24(8):1949-1957.e6.
PMID: 30134157
Natural killer (NK) cells are innate lymphocytes that possess adaptive features, including antigen-specific clonal expansion and long-lived memory responses. Although previous work demonstrated that type I interferon (IFN) signaling is...
5.
Lau C, Adams N, Geary C, Weizman O, Rapp M, Pritykin Y, et al.
Nat Immunol
. 2018 Aug;
19(9):963-972.
PMID: 30082830
Clonal expansion and immunological memory are hallmark features of the mammalian adaptive immune response and essential for prolonged host control of pathogens. Recent work demonstrates that natural killer (NK) cells...
6.
Adams N, Lau C, Fan X, Rapp M, Geary C, Weizman O, et al.
Immunity
. 2018 Jun;
48(6):1172-1182.e6.
PMID: 29858012
Natural killer (NK) cells are innate lymphocytes that display features of adaptive immunity during viral infection. Biallelic mutations in IRF8 have been reported to cause familial NK cell deficiency and...
7.
Madera S, Geary C, Lau C, Pikovskaya O, Reiner S, Sun J
J Immunol
. 2018 Feb;
200(6):1977-1981.
PMID: 29440505
The T-box transcription factors T-bet and Eomesodermin (Eomes) instruct discrete stages in NK cell development. However, their role in the immune response of mature NK cells against pathogens remains unexplored....
8.
Rapp M, Lau C, Adams N, Weizman O, OSullivan T, Geary C, et al.
Sci Immunol
. 2017 Dec;
2(18).
PMID: 29222089
Natural killer (NK) cells are innate lymphocytes that have features of adaptive immunity such as clonal expansion and generation of long-lived memory. Interleukin-12 (IL-12) signaling through its downstream transcription factor...
9.
Geary C, Sun J
Semin Immunol
. 2017 Sep;
31:11-19.
PMID: 28863960
Natural killer (NK) cells have traditionally been classified as a cellular component of the innate immune system, given their ability to rapidly produce effector cytokines and kill infected or transformed...
10.
Adams N, OSullivan T, Geary C, Karo J, Amezquita R, Joshi N, et al.
J Immunol
. 2016 Nov;
197(8):2963-2970.
PMID: 27824591
Immunological memory has traditionally been regarded as a unique trait of the adaptive immune system. Nevertheless, there is evidence of immunological memory in lower organisms and invertebrates, which lack an...