Nicholas M Adams
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Explore the profile of Nicholas M Adams including associated specialties, affiliations and a list of published articles.
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45
Citations
1278
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Recent Articles
1.
Wethington D, Ahmad S, Potempa M, Giuliani G, Aguilar O, Poudel M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060511
Natural killer (NK) cells are classically defined as innate immune cells, but experiments show that mouse cytomegalovirus (MCMV) infection in C57BL/6 mice can cause NK cells to undergo antigen-specific proliferation...
2.
Adams N, Galitsyna A, Tiniakou I, Esteva E, Lau C, Reyes J, et al.
bioRxiv
. 2024 Sep;
PMID: 39345451
The cohesin protein complex extrudes chromatin loops, stopping at CTCF-bound sites, to organize chromosomes into topologically associated domains, yet the biological implications of this process are poorly understood. We show...
3.
Adams N, Das A, Yun T, Reizis B
Annu Rev Immunol
. 2024 Jun;
42(1):347-373.
PMID: 38941603
Plasmacytoid dendritic cells (pDCs) represent a unique cell type within the innate immune system. Their defining property is the recognition of pathogen-derived nucleic acids through endosomal Toll-like receptors and the...
4.
Tiniakou I, Hsu P, Lopez-Zepeda L, Garipler G, Esteva E, Adams N, et al.
Sci Immunol
. 2024 Apr;
9(94):eadi1023.
PMID: 38608038
The development of dendritic cells (DCs), including antigen-presenting conventional DCs (cDCs) and cytokine-producing plasmacytoid DCs (pDCs), is controlled by the growth factor Flt3 ligand (Flt3L) and its receptor Flt3. We...
5.
Feng J, Jang G, Esteva E, Adams N, Jin H, Reizis B
Proc Natl Acad Sci U S A
. 2024 Jan;
121(4):e2317929121.
PMID: 38227649
The hierarchical model of hematopoiesis posits that self-renewing, multipotent hematopoietic stem cells (HSCs) give rise to all blood cell lineages. While this model accounts for hematopoiesis in transplant settings, its...
6.
Pearlman S, Leelawong M, Richardson K, Adams N, Russ P, Pask M, et al.
ACS Appl Mater Interfaces
. 2023 Dec;
16(1):1953.
PMID: 38126871
No abstract available.
7.
Sulczewski F, Maqueda-Alfaro R, Alcantara-Hernandez M, Perez O, Saravanan S, Yun T, et al.
Nat Immunol
. 2023 Jul;
24(8):1265-1280.
PMID: 37414907
High-dimensional approaches have revealed heterogeneity amongst dendritic cells (DCs), including a population of transitional DCs (tDCs) in mice and humans. However, the origin and relationship of tDCs to other DC...
8.
Jang G, Contreras Castillo S, Esteva E, Upadhaya S, Feng J, Adams N, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(22):e2302019120.
PMID: 37216517
Mammalian aging is associated with multiple defects of hematopoiesis, most prominently with the impaired development of T and B lymphocytes. This defect is thought to originate in hematopoietic stem cells...
9.
Victoriano C, Pask M, Malofsky N, Seegmiller A, Simmons S, Schmitz J, et al.
Sci Rep
. 2022 Jul;
12(1):11756.
PMID: 35817781
PCR-based diagnostics generally require nucleic acid extraction from patient specimens prior to amplification. As highlighted early in the COVID-19 pandemic, extraction steps may be difficult to scale during times of...
10.
Feng J, Pucella J, Jang G, Alcantara-Hernandez M, Upadhaya S, Adams N, et al.
Immunity
. 2022 Feb;
55(3):405-422.e11.
PMID: 35180378
Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs, comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear. We studied DC development in unmanipulated adult mice using...