Cindy N Roy
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Explore the profile of Cindy N Roy including associated specialties, affiliations and a list of published articles.
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35
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1497
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Recent Articles
21.
Steinbicker A, Sachidanandan C, Vonner A, Yusuf R, Deng D, Lai C, et al.
Blood
. 2011 Mar;
117(18):4915-23.
PMID: 21393479
Anemia of inflammation develops in settings of chronic inflammatory, infectious, or neoplastic disease. In this highly prevalent form of anemia, inflammatory cytokines, including IL-6, stimulate hepatic expression of hepcidin, which...
22.
Roy C
Hematology Am Soc Hematol Educ Program
. 2011 Jan;
2010:276-80.
PMID: 21239806
Inflammation arising from various etiologies, including infection, autoimmune disorders, chronic diseases, and aging, can promote anemia. The anemia of inflammation (AI) is most often normocytic and normochromic and is usually...
23.
Gardenghi S, Ramos P, Marongiu M, Melchiori L, Breda L, Guy E, et al.
J Clin Invest
. 2010 Nov;
120(12):4466-77.
PMID: 21099112
Excessive iron absorption is one of the main features of β-thalassemia and can lead to severe morbidity and mortality. Serial analyses of β-thalassemic mice indicate that while hemoglobin levels decrease...
24.
Roy C
Clin Geriatr Med
. 2010 Nov;
27(1):67-78.
PMID: 21093723
Although anemia is regarded as a relatively common occurrence in older adults, the vigor with which the medical community should intervene to correct this common problem is disputed. Epidemiologic data...
25.
Semba R, Patel K, Ferrucci L, Sun K, Roy C, Guralnik J, et al.
Clin Nutr
. 2010 Mar;
29(5):600-4.
PMID: 20334961
Background & Aims: Red cell distribution width (RDW), a measure of heterogeneity in the size of circulating erythrocytes, is associated with some chronic diseases and predicts mortality. Although oxidative damage...
26.
Tanaka T, Roy C, Yao W, Matteini A, Semba R, Arking D, et al.
Blood
. 2009 Nov;
115(1):94-6.
PMID: 19880490
To investigate genetic variants that affect iron concentrations in persons not affected by overt genetic disorders of iron metabolism, a genome-wide association study was conducted in the InCHIANTI Study (N...
27.
Roy C, Mak H, Akpan I, Losyev G, Zurakowski D, Andrews N
Blood
. 2007 Jan;
109(9):4038-44.
PMID: 17218383
The anemia of inflammation is an acquired disorder affecting patients with a variety of medical conditions, and it is characterized by changes in iron homeostasis and erythropoiesis. Mounting evidence suggests...
28.
Donovan A, Roy C, Andrews N
Physiology (Bethesda)
. 2006 Mar;
21:115-23.
PMID: 16565477
Iron is an essential element that is toxic when it accumulates in excess. Intricate regulatory mechanisms have evolved to maintain iron homeostasis within cells and between different tissues of complex...
29.
Roy C, Andrews N
Curr Opin Hematol
. 2005 Feb;
12(2):107-11.
PMID: 15725899
Purpose Of Review: The anemia of inflammation has been associated for nearly two decades with elevated cytokine levels, but the primary mediator of this condition was unknown. Recently hepcidin antimicrobial...
30.
Roy C, Custodio A, de Graaf J, Schneider S, Akpan I, Montross L, et al.
Nat Genet
. 2004 Apr;
36(5):481-5.
PMID: 15098034
Inflammation influences iron balance in the whole organism. A common clinical manifestation of these changes is anemia of chronic disease (ACD; also called anemia of inflammation). Inflammation reduces duodenal iron...