Chris Cheadle
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Explore the profile of Chris Cheadle including associated specialties, affiliations and a list of published articles.
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58
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2727
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Recent Articles
1.
Richman S, Lyman C, Nesterova A, Yuryev A, Morris M, Cao H, et al.
NPJ Syst Biol Appl
. 2022 Oct;
8(1):38.
PMID: 36216820
A major complication in COVID-19 infection consists in the onset of acute respiratory distress fueled by a dysregulation of the host immune network that leads to a run-away cytokine storm....
2.
Boorgula M, Taub M, Rafaels N, Daya M, Campbell M, Chavan S, et al.
Clin Epigenetics
. 2019 Aug;
11(1):122.
PMID: 31443688
Background: Although epigenetic mechanisms are important risk factors for allergic disease, few studies have evaluated DNA methylation differences associated with atopic dermatitis (AD), and none has focused on AD with...
3.
Xu C, Cao H, Zhang F, Cheadle C
Int J Mol Med
. 2018 Sep;
42(5):2353-2362.
PMID: 30226572
Previous studies have indicated that genetic factors are the predominate cause of Autism spectrum disorder (ASD). Nevertheless, to the best of our knowledge, to date no systematic study has summarized...
4.
Cheadle C, Cao H, Kalinin A, Hodgkinson J
Ann N Y Acad Sci
. 2016 Nov;
1387(1):25-33.
PMID: 27859320
Comprehensive data mining of the scientific literature has become an increasing challenge. To address this challenge, Elsevier's Pathway Studio software uses the techniques of natural language processing to systematically extract...
5.
Ascierto M, McMiller T, Berger A, Danilova L, Anders R, Netto G, et al.
Cancer Immunol Res
. 2016 Aug;
4(9):726-33.
PMID: 27491898
Pretreatment tumor PD-L1 expression has been shown to correlate with response to anti-PD-1/PD-L1 therapies. Yet, most patients with PD-L1(+) tumors do not respond to treatment. The current study was undertaken...
6.
Bouquet J, Soloski M, Swei A, Cheadle C, Federman S, Billaud J, et al.
mBio
. 2016 Feb;
7(1):e00100-16.
PMID: 26873097
Unlabelled: Lyme disease is a tick-borne illness caused by the bacterium Borrelia burgdorferi, and approximately 10 to 20% of patients report persistent symptoms lasting months to years despite appropriate treatment...
7.
Gao L, Emond M, Louie T, Cheadle C, Berger A, Rafaels N, et al.
Arthritis Rheumatol
. 2015 Oct;
68(1):191-200.
PMID: 26473621
Objective: To determine the contribution of rare variants as genetic modifiers of the expressivity, penetrance, and severity of systemic sclerosis (SSc). Methods: We performed whole-exome sequencing of 78 European American...
8.
Ma J, Chen C, Barth A, Cheadle C, Guan X, Gao L
Mediators Inflamm
. 2015 Jun;
2015:984825.
PMID: 26063982
Background: Sepsis is a leading cause of mortality in intensive care units worldwide. A better understanding of the blood systems response to sepsis should expedite the identification of biomarkers for...
9.
Zhao X, Fan J, Zhi F, Li A, Li C, Berger A, et al.
Hum Mol Genet
. 2015 Jun;
24(16):4615-24.
PMID: 26034135
Ulcerative colitis (UC) is a chronic, relapsing and debilitating idiopathic inflammation, with variable and complex pathophysiologies. Our objective was to elucidate patterns of gene expression underlying the progression of UC...
10.
Taube J, Young G, McMiller T, Chen S, Salas J, Pritchard T, et al.
Clin Cancer Res
. 2015 May;
21(17):3969-76.
PMID: 25944800
Purpose: Blocking the immunosuppressive PD-1/PD-L1 pathway has antitumor activity in multiple cancer types, and PD-L1 expression on tumor cells and infiltrating myeloid cells correlates with the likelihood of response. We...