Chyi-Song Hsieh
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Explore the profile of Chyi-Song Hsieh including associated specialties, affiliations and a list of published articles.
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5251
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Recent Articles
1.
Srivastava N, Vomund A, Peterson O, Abousaway O, Li T, Kain L, et al.
bioRxiv
. 2024 Nov;
PMID: 39605669
Type 1 diabetes (T1D) affects a genetically susceptible population that develops autoreactive T cells attacking insulin-producing pancreatic β cells. Increasingly, neoantigens are recognized as critical drivers of this autoimmune response....
2.
Hu H, Vomund A, Peterson O, Srivastava N, Li T, Kain L, et al.
Nat Commun
. 2024 Sep;
15(1):8318.
PMID: 39333495
Autoimmune attack toward pancreatic β cells causes permanent loss of glucose homeostasis in type 1 diabetes (T1D). Insulin secretory granules store and secrete insulin but are also thought to be...
3.
Ver Heul A, Mack M, Zamidar L, Tamari M, Yang T, Trier A, et al.
bioRxiv
. 2024 May;
PMID: 38712036
Antigen specificity is the central trait distinguishing adaptive from innate immune function. Assembly of antigen-specific T cell and B cell receptors occurs through V(D)J recombination mediated by the Recombinase Activating...
4.
Kulkarni D, Talati K, Joyce E, Kousik H, Harris D, Floyd A, et al.
bioRxiv
. 2024 Jan;
PMID: 38260555
Humoral immune responses within the gut play diverse roles including pathogen clearance during enteric infections, maintaining tolerance, and facilitating the assemblage and stability of the gut microbiota. How these humoral...
5.
Piersma S, Bangru S, Yoon J, Liu T, Yang L, Hsieh C, et al.
J Exp Med
. 2023 Sep;
220(11).
PMID: 37698554
Natural killer (NK) cells are lymphocytes capable of controlling tumors and virus infections through direct lysis and cytokine production. While both T and NK cells expand and accumulate in affected...
6.
Yi J, Hsieh C
J Exp Med
. 2022 Dec;
220(2).
PMID: 36520516
In this issue of JEM, Tanaka et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20220386) advance our understanding of how genetic mutants that decrease T cell recognition of antigen, a critical event for...
7.
Yi J, Miller A, Archambault A, Jones A, Bradstreet T, Bandla S, et al.
Sci Immunol
. 2022 Oct;
7(76):eabo0777.
PMID: 36206355
Both higher- and lower-affinity self-reactive CD4 T cells are expanded in autoimmunity; however, their individual contribution to disease remains unclear. We addressed this question using peptide-MHCII chimeric antigen receptor (pMHCII-CAR)...
8.
Jaeger N, McDonough R, Rosen A, Hernandez-Leyva A, Wilson N, Lint M, et al.
Cell Rep
. 2022 Jan;
38(4):110324.
PMID: 35081343
No abstract available.
9.
Udayan S, Stamou P, Crispie F, Hickey A, Floyd A, Hsieh C, et al.
Gut Microbes
. 2022 Jan;
14(1):2007743.
PMID: 35023810
In healthy hosts the gut microbiota is restricted to gut tissues by several barriers some of which require MyD88-dependent innate immune sensor pathways. Nevertheless, some gut taxa have been reported...
10.
Czepielewski R, Erlich E, Onufer E, Young S, Saunders B, Han Y, et al.
Immunity
. 2021 Nov;
54(12):2795-2811.e9.
PMID: 34788601
Lymphangitis and the formation of tertiary lymphoid organs (TLOs) in the mesentery are features of Crohn's disease. Here, we examined the genesis of these TLOs and their impact on disease...