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Jiani N Chai

Explore the profile of Jiani N Chai including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 843
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Recent Articles
1.
Modi M, Kiszluk A, Chai J, Edema U, Ma M, Sica R, et al.
Am J Clin Pathol . 2023 Oct; 161(2):140-148. PMID: 37830309
Objectives: Adult T-cell leukemia/lymphoma (ATLL) is a rare aggressive T-cell leukemia/lymphoma associated with human T lymphotropic virus type 1 infection. The patients might present with skin rash before, at, or...
2.
Chai J, Azad A, Kuan K, Guo X, Wang Y
Hematol Rep . 2022 Jun; 14(2):172-178. PMID: 35735736
Congenital CD59 deficiency is a recently described rare autosomal recessive disease associated with CD59 gene mutations that lead to deficient or dysfunctional CD59 protein on the cell surface. The disease...
3.
Jaeger N, McDonough R, Rosen A, Hernandez-Leyva A, Wilson N, Lint M, et al.
Cell Rep . 2022 Jan; 38(4):110324. PMID: 35081343
No abstract available.
4.
Russler-Germain E, Jung J, Miller A, Young S, Yi J, Wehmeier A, et al.
Immunity . 2021 Oct; 54(11):2547-2564.e7. PMID: 34715017
Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of Cryptosporidium tyzzeri (Ct-STL) serendipitously discovered when conventional...
5.
Russler-Germain E, Yi J, Young S, Nutsch K, Wong H, Ai T, et al.
Elife . 2021 Feb; 10. PMID: 33533717
Generation of tolerogenic peripheral regulatory T (pTreg) cells is commonly thought to involve CD103 gut dendritic cells (DCs), yet their role in commensal-reactive pTreg development is unclear. Using two Helicobacterspecific...
6.
Wang F, Trier A, Li F, Kim S, Chen Z, Chai J, et al.
Cell . 2021 Jan; 184(2):422-440.e17. PMID: 33450207
Itch is an evolutionarily conserved sensation that facilitates expulsion of pathogens and noxious stimuli from the skin. However, in organ failure, cancer, and chronic inflammatory disorders such as atopic dermatitis...
7.
Rengarajan S, Knoop K, Rengarajan A, Chai J, Grajales-Reyes J, Samineni V, et al.
Cell Rep Med . 2020 Nov; 1(7). PMID: 33196055
Stress is a known trigger for flares of inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS); however, this process is not well understood. Here, we find that restraint stress...
8.
Jaeger N, McDonough R, Rosen A, Hernandez-Leyva A, Wilson N, Lint M, et al.
Cell Rep . 2020 Nov; 33(5):108331. PMID: 33147448
Homeostatic mucosal immune responses are fine-tuned by naturally evolved interactions with native microbes, and integrating these relationships into experimental models can provide new insights into human diseases. Here, we leverage...
9.
Cervantes-Barragan L, Cortez V, Wang Q, McDonald K, Chai J, Luccia B, et al.
Front Immunol . 2019 Jul; 10:1423. PMID: 31312200
The gastrointestinal tract hosts the largest collection of commensal microbes in the body. Infections at this site can cause significant perturbations in the microbiota, known as dysbiosis, that facilitate the...
10.
Zhu Z, Gorman M, McKenzie L, Chai J, Hubert C, Prager B, et al.
J Exp Med . 2017 Sep; 214(10):3145. PMID: 28916645
No abstract available.