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Chung-Eun Ha

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Articles 22
Citations 310
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Recent Articles
11.
Yang J, Ha C, Bhagavan N
Biochim Biophys Acta . 2005 May; 1724(1-2):37-48. PMID: 15913893
Site-directed mutagenesis was used to study the role of histidine residues located in domain I in the neutral-to-basic (N-B) transition of human serum albumin (HSA). Based on a previous study...
12.
Liu R, Yang J, Ha C, Bhagavan N, Eckenhoff R
Biochem J . 2005 Jan; 388(Pt 1):39-45. PMID: 15634193
Multiple binding sites for anaesthetics in HSA (human serum albumin) make solution studies difficult to interpret. In the present study, we expressed the wild-type HSA domain 3 (wtHSAd3), a peptide...
13.
Siemiarczuk A, Petersen C, Ha C, Yang J, Bhagavan N
Cell Biochem Biophys . 2004 Apr; 40(2):115-22. PMID: 15054218
Tryptophan 214, the only tryptophan residue in human serum albumin, is located in the physiologically important subdomain 2A ligand binding site. In the present study the fluorescence lifetime of tryptophan...
14.
Liu R, Meng Q, Xi J, Yang J, Ha C, Bhagavan N, et al.
Biochem J . 2004 Feb; 380(Pt 1):147-52. PMID: 14759223
Propofol and halothane are clinically used general anaesthetics, which are transported primarily by HSA (human serum albumin) in the blood. Binding characteristics are therefore of interest for both the pharmacokinetics...
15.
Petitpas I, Petersen C, Ha C, Bhattacharya A, Zunszain P, Ghuman J, et al.
Proc Natl Acad Sci U S A . 2003 May; 100(11):6440-5. PMID: 12743361
Human serum albumin (HSA) is the major protein component of blood plasma and serves as a transporter for thyroxine and other hydrophobic compounds such as fatty acids and bilirubin. We...
16.
Ha J, Ha C, Chao J, Petersen C, Theriault A, Bhagavan N
Biochim Biophys Acta . 2003 May; 1640(2-3):119-28. PMID: 12729921
In the present study, we used the human EA.hy926 endothelial cell line as the model system to investigate the effect of human serum albumin (HSA) and its structural variants on...
17.
Bhagavan N, Lai E, Rios P, Yang J, Ortega-Lopez A, Shinoda H, et al.
Clin Chem . 2003 Mar; 49(4):581-5. PMID: 12651810
Background: Clinical diagnoses were correlated with results of a Co(II)-albumin binding assay in 167 patients treated at an emergency department of a health maintenance organization. Methods: Patients were evaluated as...
18.
Liu R, Pidikiti R, Ha C, Petersen C, Bhagavan N, Eckenhoff R
J Biol Chem . 2002 Jul; 277(39):36373-9. PMID: 12118010
Electrostatic interactions have been proposed as a potentially important force for anesthetics and protein binding but have not yet been tested directly. In the present study, we used wild-type human...
19.
Petersen C, Ha C, Curry S, Bhagavan N
Proteins . 2002 Apr; 47(2):116-25. PMID: 11933059
The binding of warfarin to the following human serum albumin (HSA) mutants was examined: K195M, K199M, F211V, W214L, R218M, R222M, H242V, and R257M. Warfarin bound to human serum albumin (HSA)...
20.
Subramaniam R, Fan X, Scivittaro V, Yang J, Ha C, Petersen C, et al.
Arch Biochem Biophys . 2002 Mar; 400(1):15-25. PMID: 11913966
In order to understand the mechanism by which advanced glycation endproducts (AGEs) elicit oxidative stress, macrophage-like RAW264.7 cells were exposed to various AGE-albumins, and oxidant stress was estimated from the...